Naloxone methiodide
Naloxone methiodide (CAS: 93302-47-7), with the empirical formula C20H24INO4 and a molecular weight of 469.31 g/mol, is a quaternary ammonium compound. It presents as a white to tan solid and is a potent opioid antagonist. This compound is primarily utilised in research settings, particularly within neurobiology and cell signalling studies, to investigate the effects of opioid receptor interactions.
- IUPAC
- (5α,17R)-4,5-Epoxy-3,14-dihydroxy-17-methyl-6-oxo-17-(2-propenyl)-morphinanium iodide,N-Methylnaloxonium iodide
Opioid Receptor Research
Naloxone methiodide serves as a vital tool in understanding the complex mechanisms of opioid receptors. Its antagonist properties allow researchers to block opioid effects, facilitating studies into receptor binding and downstream signalling pathways.
Neuroscience Investigations
Within neuroscience, this compound aids in the exploration of pain pathways, addiction research, and the physiological effects of endogenous and exogenous opioids. It helps delineate the roles of various receptor subtypes.
Biochemical Assays
As a bioactive small molecule, Naloxone methiodide is employed in biochemical assays to test for opioid antagonist activity or to study drug interactions within cellular systems. Its defined chemical structure makes it a reliable reagent for these purposes.
| Molecular weight | 469.31 |
|---|---|
| Empirical formula | C20H24INO4 |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to tan |
| Solubility | H2O: >10 mg/mL |
| Storage temperature | 2-8°C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Naloxone methiodide used for?
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Naloxone methiodide is used in research, particularly in neurobiology and cell signalling, to investigate opioid receptor interactions and effects. It acts as an opioid antagonist.
What is the CAS number and formula for Naloxone methiodide?
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The CAS number for Naloxone methiodide is 93302-47-7, and its empirical formula is C20H24INO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Naloxone methiodide with a purity of ≥98% (HPLC). This product is not represented as USP, BP, or EP grade.
How should Naloxone methiodide be handled safely?
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Naloxone methiodide is a Warning substance with H315, H319, and H335 hazard statements. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation. Store at 2-8°C.
Is Naloxone methiodide a controlled substance?
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Yes, Naloxone methiodide is regulated under CDSA and is not available from Canada.
How is Naloxone methiodide shipped or exported?
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Shipments and exports of Naloxone methiodide comply with all relevant regulations for controlled substances and hazardous materials.
How can I request a quote or sample for Naloxone methiodide?
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To request a quote or sample, please contact our sales team with your specific requirements and shipping details.
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