Nalorphine hydrochloride
Nalorphine hydrochloride (CAS: 57-29-4), with the molecular formula C19H21NO3 · HCl and a molecular weight of 347.84 g/mol, is a synthetic opioid antagonist. It functions as a kappa-opioid receptor agonist and mu-opioid receptor antagonist. Nalorphine hydrochloride is utilized in research settings for its unique pharmacological properties, particularly in studies related to pain perception and opioid receptor interactions.
- IUPAC
- N-Allylnormorphine HCl,Nalline HCl
- Synonyms
- N-Allylnormorphine HCl,Nalline HCl

Opioid Receptor Research
Serves as a valuable tool in pharmacological studies investigating the complex mechanisms of opioid receptors, aiding in the understanding of their roles in pain and addiction.
Neuroscience Research
Utilised in neurobiological research to explore the signaling pathways and functional outcomes associated with the activation and blockade of specific opioid receptor subtypes.
GPCR Modulation Studies
Employed in the study of G protein-coupled receptors (GPCRs), particularly within the opioid receptor family, to understand ligand binding and downstream signaling events.
| Molecular weight | 347.84 |
|---|---|
| Empirical formula | C19H21NO3 · HCl |
| Form | solid |
| Colour | white |
| Solubility | H2O: slightly solubledilute aqueous acid: solubleethanol: soluble |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | USDEA Schedule III; regulated under CDSA - not available from Canada |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Nalorphine hydrochloride used for?
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Nalorphine hydrochloride is primarily used in research settings for its pharmacological properties as an opioid receptor antagonist and agonist, particularly in studies of pain, addiction, and neuroscience.
What is the CAS number and formula for Nalorphine hydrochloride?
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The CAS number for Nalorphine hydrochloride is 57-29-4, and its empirical formula is C19H21NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Nalorphine hydrochloride with a typical purity assay. It is supplied for research and laboratory use. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should Nalorphine hydrochloride be handled safely?
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Nalorphine hydrochloride is classified as harmful if swallowed (H302). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation.
Is Nalorphine hydrochloride a controlled substance?
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Yes, Nalorphine hydrochloride is a US DEA Schedule III controlled substance and is regulated under the CDSA in Canada, though it is not available from Canada via TSS.
How is Nalorphine hydrochloride shipped?
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Nalorphine hydrochloride is carefully packed and exported by Tech Serve Solutions in compliance with all relevant shipping and regulatory requirements for controlled substances.
How can I request a quote or sample for Nalorphine hydrochloride?
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To request a quote or sample for Nalorphine hydrochloride, please contact our sales department via our website or by phone.
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