N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt (CAS: 16980-89-5) is a cell-permeable analogue of cyclic AMP. It effectively activates the cyclic AMP-dependent protein kinase (PKA) and the associated signaling pathway. This compound serves as a valuable tool in cell biology research, particularly for studies involving morphological differentiation and cell signaling modulation, finding applications in neural differentiation research.
- IUPAC
- Bucladesine sodium salt,Dibutyryl cAMP sodium salt,Dibutyryl cyclic-AMP sodium salt
- Synonyms
- 16980-89-5C18H23N5O8PNaBucladesine sodium saltDibutyryl cAMP sodium saltDibutyryl cyclic-AMP sodium salt
Cell Signaling and Neuroscience Research
Dibutyryl cAMP sodium salt acts as a cell-permeable analogue to activate the cAMP/PKA signaling pathway. It is widely used in neuroscience research for studying neural differentiation and cell signaling modulation.
Morphological Differentiation Studies
This compound is employed as an inducer of morphological differentiation in various cell types, including Schwann cells. Its ability to modulate cell signaling makes it a key reagent for these studies.
Biochemical Research
As a stable and cell-permeable cyclic nucleotide analogue, it facilitates research into cyclic AMP-dependent processes and enzyme activation, particularly protein kinase A.
| Molecular weight | 491.37 |
|---|---|
| Linear formula | C18H23N5O8PNa |
| Assay | ≥97% (HPLC) |
| Form | powder |
| Colour | off-white |
| Solubility | H2O: soluble100 mg/mL |
| Storage temperature | −20°C |
| Impurities tested | ≤0.5% cyclic AMP and 2′-O-monobutyryl-cyclic AMP≤3% N6-monobutyryl-cyclic AMP |
| Application | Dibutyryl cAMP is a cell-permeable cAMP analogue that activates cAMP dependent protein kinase (PKA) or the cAMP/PKA signaling pathway. Dibutyryl cAMP is used as a morphological differentiation inducer and cell signaling modulator in cells such as Schwann cells. It is used in a variety of neural differentiation studies. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt used for?
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It is used as a cell-permeable analogue to activate the cAMP/PKA signaling pathway, induce morphological differentiation, and modulate cell signaling in research, particularly in neuroscience.
What is the CAS number and formula for N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt?
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The CAS number is 16980-89-5, and the linear formula is C18H23N5O8PNa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt with an assay of ≥97% (HPLC). This product is intended for research purposes and is not supplied as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for this compound?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter, should be used. Refer to the safety data sheet for full handling information. The WGK (Germany) is 2.
How is N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt packed, shipped, and exported?
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This product is typically stored at -20°C and shipped according to standard chemical handling protocols. Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals.
How can I request a sample or a quote for N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt?
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Please contact our sales team directly through our website or by phone to request a sample or obtain a quotation for N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt.
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