N4-Octadecylcytosine β-D-arabinofuranoside
N4-Octadecylcytosine β-D-arabinofuranoside (CAS: 158233-67-1) is a lipophilic derivative of Cytarabine (Ara-C) with the molecular formula C27H49N3O5. This compound is engineered to enhance the incorporation of Ara-C, a known anti-cancer agent, into lipid bilayers of liposomes and directly into target cells. Its specific structure facilitates improved cellular uptake and delivery, making it a valuable tool in research related to targeted cancer therapies.
- IUPAC
- N(4)-octadecyl-ara-C,N4-Stearyl-Ara C,NOAC
- Synonyms
- N4-Stearyl-Ara CN(4)-octadecyl-ara-CNOAC

Lipid Bilayer Incorporation
N4-Octadecylcytosine β-D-arabinofuranoside is utilised to improve the integration of the anti-cancer agent Cytarabine into the lipid bilayers of liposomes. This enhances the stability and delivery efficiency of liposomal drug formulations.
Cellular Uptake Enhancement
As a lipophilic derivative, this compound aids in the improved incorporation and delivery of Cytarabine into target cells. This mechanism is crucial for enhancing the efficacy of cancer therapies that rely on intracellular drug action.
Nucleoside Analog Research
This molecule serves as a key research chemical within the study of nucleoside analogs. Its unique structure allows for investigations into drug delivery systems and the development of novel therapeutic strategies.
| Molecular weight | 495.70 |
|---|---|
| Empirical formula | C27H49N3O5 |
| Application | N4-Stearyl-Ara C (N(4)-octadecyl-ara-C, NOAC) is a lipophilic derivative of Ara-C used to improve the incorporation of Ara-C, an anti-cancer agent, into lipid bilayers of liposomes and/or target cells. |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N4-Octadecylcytosine β-D-arabinofuranoside used for?
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N4-Octadecylcytosine β-D-arabinofuranoside is used to improve the incorporation of the anti-cancer agent Ara-C into lipid bilayers of liposomes and into target cells, enhancing its delivery and efficacy.
What is the CAS number and molecular formula for N4-Octadecylcytosine β-D-arabinofuranoside?
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The CAS number is 158233-67-1, and the molecular formula is C27H49N3O5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and laboratory use. The specific assay and grade are available on the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.
How should N4-Octadecylcytosine β-D-arabinofuranoside be handled?
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Based on its safety data, handle with appropriate personal protective equipment. Refer to the Safety Data Sheet (SDS) for detailed handling, storage, and disposal information. The WGK Germany classification is 3.
Is this chemical a controlled substance?
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The provided data does not indicate that N4-Octadecylcytosine β-D-arabinofuranoside is a controlled substance.
How is N4-Octadecylcytosine β-D-arabinofuranoside packed and shipped?
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Tech Serve Solutions packs and ships chemicals in compliance with all relevant regulations for domestic and international transport. Please contact us for specific shipping inquiries.
How can I request a sample or quote?
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To request a sample or a formal quotation, please use the contact form on our website or reach out to our sales department directly via email or phone.
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