N-Tosylaziridine
N-Tosylaziridine (CAS: 3634-89-7; Formula: C9H11NO2S; MW: 197.25) is a valuable organic building block, primarily recognised for its role as a reagent in beta-aminoethylation reactions. This compound serves as a key intermediate in various chemical synthesis pathways, offering researchers and industrial chemists a reliable tool for introducing specific functional groups. Its well-defined structure and reactivity make it an important component in the development of complex organic molecules.
- IUPAC
- N-(p-Toluenesulfonyl)aziridine,N-(p-Tolylsulfonyl)aziridine
- Synonyms
- N-(p-Toluenesulfonyl)aziridineN-(p-Tolylsulfonyl)aziridine

Beta-Aminoethylation Reagent
N-Tosylaziridine is effectively employed as a reagent for the beta-aminoethylation of various nucleophiles. This process allows for the introduction of a protected aminoethyl moiety, which can be crucial in the synthesis of pharmaceuticals and other complex organic compounds.
Organic Synthesis Building Block
As a versatile building block, N-Tosylaziridine participates in diverse organic synthesis strategies. Its aziridine ring, activated by the tosyl group, readily undergoes ring-opening reactions, facilitating the construction of nitrogen-containing heterocycles and other sophisticated molecular architectures.
Intermediate in Fine Chemical Production
The compound finds application as an intermediate in the production of fine chemicals. Its reactivity profile makes it suitable for incorporation into multi-step syntheses where precise control over functional group introduction is required.
| Molecular weight | 197.25 |
|---|---|
| Empirical formula | C9H11NO2S |
| Assay | ≥98.0% (HPLC)98% |
| Storage temperature | −20°C |
| Application | Reagent for beta-aminoethylation1,2 |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Tosylaziridine used for?
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N-Tosylaziridine is primarily used as a reagent for beta-aminoethylation reactions and as a versatile building block in organic synthesis.
What is the CAS number and formula for N-Tosylaziridine?
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The CAS number for N-Tosylaziridine is 3634-89-7, and its molecular formula is C9H11NO2S.
What grade and purity does Tech Serve Solutions supply for N-Tosylaziridine?
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Tech Serve Solutions supplies N-Tosylaziridine with an assay of ≥98.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade; it is suitable for research and technical applications.
How should N-Tosylaziridine be handled safely?
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N-Tosylaziridine is classified as a Warning substance. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, should be worn. Ensure good ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do. Continue rinsing.
How is N-Tosylaziridine typically stored and shipped?
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N-Tosylaziridine should be stored at -20°C. Tech Serve Solutions can export this chemical globally, adhering to all relevant shipping and handling regulations.
How can I request a quote or sample of N-Tosylaziridine?
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To request a quote or a sample of N-Tosylaziridine, please contact the Tech Serve Solutions sales department via our website or by phone. Specify the quantity and your delivery requirements.
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