N,N-Dimethyltrimethylsilylamine
N,N-Dimethyltrimethylsilylamine (CAS 2083-91-2) is a colourless liquid with the molecular formula (CH3)3SiN(CH3)2 and a molecular weight of 117.26 g/mol. It is a valuable silylation reagent utilised in organic synthesis and analytical chemistry. This compound serves as a building block and derivatization agent, particularly for enhancing volatility in gas chromatography.
- IUPAC
- (Dimethylamino)trimethylsilane,N-(Trimethylsilyl)dimethylamine,TMSDMA
- Synonyms
- (CH3)3SiN(CH3)2(Dimethylamino)trimethylsilaneN-(Trimethylsilyl)dimethylamineTMSDMA

Silylation Reagent
N,N-Dimethyltrimethylsilylamine is commonly employed as a silylating agent in organic chemistry. It effectively introduces trimethylsilyl groups onto molecules, modifying their properties for further reactions or analysis.
Derivatization for Chromatography
This compound is used to derivatize analytes, especially those with polar functional groups, to increase their volatility and thermal stability. This application is crucial for successful gas chromatography (GC) analysis.
Organic Synthesis Building Block
As a nitrogen-containing organosilicon compound, it functions as a versatile building block in the synthesis of more complex organic molecules and organometallic compounds.
Analytical Chemistry
Its ability to derivatize compounds makes it a useful reagent in analytical laboratories for sample preparation and the identification of various substances.
| Molecular weight | 117.26 |
|---|---|
| Linear formula | (CH3)3SiN(CH3)2 |
| Assay | ≥95.0% (GC) |
| Grade | purum |
| Boiling point | 84 °C(lit.) |
| Density | 0.732 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.397(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -12 °C / 10.4 °F |
| Transport (UN / ADR) | UN 2733PSN1 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethyltrimethylsilylamine used for?
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N,N-Dimethyltrimethylsilylamine is primarily used as a silylating agent in organic synthesis and as a derivatization reagent to enhance the volatility and thermal stability of compounds for gas chromatography (GC).
What is the CAS number and formula for N,N-Dimethyltrimethylsilylamine?
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The CAS number is 2083-91-2, and its linear formula is (CH3)3SiN(CH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Dimethyltrimethylsilylamine at a 'purum' grade with an assay of ≥95.0% (GC). TSS does not represent this product as USP, BP, or EP grade.
How should N,N-Dimethyltrimethylsilylamine be handled safely?
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N,N-Dimethyltrimethylsilylamine is a highly flammable liquid and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Keep away from heat and ignition sources.
Is N,N-Dimethyltrimethylsilylamine available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including N,N-Dimethyltrimethylsilylamine, and can assist with international shipping requirements.
How can I request a quote or sample for N,N-Dimethyltrimethylsilylamine?
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Please contact our sales team via the website or direct inquiry to request a quote or sample of N,N-Dimethyltrimethylsilylamine.
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