N,N-Dimethyltriisopropylsilylamine
N,N-Dimethyltriisopropylsilylamine (CAS: 181231-66-3) is a silicon-based organic compound with the linear formula [(CH3)2CH]3SiN(CH3)2 and a molecular weight of 201.42 g/mol. This chemical functions as a valuable building block in organic synthesis, particularly for introducing protected amine functionalities. Its properties make it useful in various chemical synthesis applications, especially where a sterically hindered silyl amine is required.
- IUPAC
- (Dimethylamino)triisopropylsilane
- Synonyms
- [(CH3)2CH]3SiN(CH3)2(Dimethylamino)triisopropylsilane
![N,N-Dimethyltriisopropylsilylamine ([(CH3)2CH]3SiN(CH3)2) — chemical structure, CAS 181231-66-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F181231-66-3.png&w=3840&q=75)
Organic Synthesis Building Block
N,N-Dimethyltriisopropylsilylamine serves as a key intermediate in the synthesis of complex organic molecules. It is employed to introduce protected amine groups, offering a route to aminated compounds.
Protected Amine Reagent
The triisopropylsilyl group provides steric bulk and stability, making this compound suitable for protecting amine functionalities during multi-step synthetic processes. This allows for selective reactions elsewhere in the molecule.
Nitrogen Compound Synthesis
As a nitrogen-containing organic compound, it can be utilised in the development of novel nitrogenous materials and pharmaceuticals. Its specific structure facilitates unique chemical transformations.
| Molecular weight | 201.42 |
|---|---|
| Linear formula | [(CH3)2CH]3SiN(CH3)2 |
| Assay | 96% |
| Boiling point | 76-78 °C/8 mmHg(lit.) |
| Density | 0.833 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
| Melting point | 27-30 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 67 °C / 152.6 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N-Dimethyltriisopropylsilylamine used for?
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N,N-Dimethyltriisopropylsilylamine is primarily used as a building block in organic synthesis and as a reagent for introducing protected amine groups.
What is the CAS number and formula for N,N-Dimethyltriisopropylsilylamine?
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The CAS number is 181231-66-3, and the linear formula is [(CH3)2CH]3SiN(CH3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N,N-Dimethyltriisopropylsilylamine with a purity of 96%. This product is not represented as USP, BP, or EP grade.
How should N,N-Dimethyltriisopropylsilylamine be handled?
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N,N-Dimethyltriisopropylsilylamine causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation or use a suitable respirator.
Is N,N-Dimethyltriisopropylsilylamine a controlled substance?
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The provided data does not indicate that N,N-Dimethyltriisopropylsilylamine is a controlled substance.
How is N,N-Dimethyltriisopropylsilylamine packed, shipped, or exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific packing and shipping details are available upon request and comply with international regulations.
How can I request a quote or sample for N,N-Dimethyltriisopropylsilylamine?
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To request a quote or sample, please contact our sales team via the website or direct inquiry, providing your contact details and the product CAS number (181231-66-3).
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