N-Methylacetamide
N-Methylacetamide (CAS: 79-16-3), with the linear formula CH3CONHCH3 and a molecular weight of 73.09 g/mol, is an organic compound functioning as a valuable building block in chemical synthesis. It serves as a protected amine and a nitrogen-containing compound. Its primary utility lies in its role as an intermediate in various organic synthesis pathways, particularly where controlled acylation of methylamine is required.
- IUPAC
- Acetylmethylamine
- Synonyms
- AcetylmethylamineN-Acetyl-N-methylamineMethylacetamide

Organic Synthesis Intermediate
N-Methylacetamide acts as a key intermediate in the synthesis of more complex organic molecules. Its protected amine functionality allows for selective reactions, making it useful in multi-step synthetic routes.
Building Block for Nitrogen Compounds
As a nitrogen-containing organic compound, it serves as a fundamental building block for creating diverse nitrogenous structures in research and development settings.
Reagent in Amide Chemistry
Its structure makes it a suitable reagent for specific amide-related transformations and derivatisations in organic chemistry laboratories.
| Molecular weight | 73.09 |
|---|---|
| Linear formula | CH3CONHCH3 |
| Assay | ≥98.0% (GC) |
| Boiling point | 204-206 °C(lit.) |
| Density | 0.957 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.433(lit.) |
| Melting point | 26-28 °C(lit.) |

Hazard statements
- H360D
Precautionary statements
- P201Obtain special instructions before use
- P308IF exposed or concerned
| Protective equipment | Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | T |
| Risk statements (R) | 61 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Methylacetamide used for?
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N-Methylacetamide is primarily used as a building block in organic synthesis and as an intermediate for creating nitrogen-containing compounds.
What is the CAS number and formula for N-Methylacetamide?
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The CAS number for N-Methylacetamide is 79-16-3, and its linear formula is CH3CONHCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Methylacetamide with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should N-Methylacetamide be handled safely?
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N-Methylacetamide is classified as Danger (GHS08) and carries the hazard statement H360D, indicating it may damage the unborn child. Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., N100 or P3 filters), must be used. Handle only in well-ventilated areas or under a fume hood. Ensure P201 is consulted before use and P308 + P313 is followed if exposed or concerned.
Is N-Methylacetamide a controlled substance?
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The provided data does not indicate that N-Methylacetamide is a controlled substance.
How is N-Methylacetamide packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Specific packing and shipping details depend on quantity and destination, adhering to all relevant regulations.
How can I request a sample or quote for N-Methylacetamide?
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To request a sample or a quote for N-Methylacetamide, please contact our sales team through the website or by phone, providing your specific requirements.
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