N-Methyl-bis(trifluoroacetamide)
N-Methyl-bis(trifluoroacetamide), CAS 685-27-8, with the molecular formula C5H6F6N2O2 and a molar mass of 223.07 g/mol, is a high-purity reagent (≥97.0% GC) supplied by Tech Serve Solutions. This compound is primarily utilised as a derivatisation agent for introducing the trifluoroacetyl group. Its properties make it suitable for applications in chemical synthesis, particularly for the analysis of alcohols.
- IUPAC
- MBTFA
- Synonyms
- N-Methyl-bis(trifluoroacetamide)685-27-8MBTFA
Derivatisation Agent
N-Methyl-bis(trifluoroacetamide) is an effective reagent for the introduction of the trifluoroacetyl group into various molecules. This process is crucial in analytical chemistry for enhancing detectability and chromatographic separation.
Alcohol Analysis
This compound is particularly suitable for the derivatisation of alcohols. The resulting trifluoroacetyl derivatives can be more readily detected and quantified using techniques such as gas chromatography (GC).
Chemical Synthesis Building Block
As an organic building block, N-Methyl-bis(trifluoroacetamide) can be employed in various synthetic pathways requiring the incorporation of fluorinated moieties.
| Molecular weight | 223.07 |
|---|---|
| Linear formula | CF3CON(CH3)COCF3 |
| Assay | ≥97.0% (GC) |
| Grade | purum |
| Boiling point | 121-122 °C(lit.) |
| Density | 1.547 g/mL at 25 °C |
| Refractive index | n20/D 1.346(lit.)n20/D 1.346 |
| Application | Reagent for introducing trifluoroacetyl group. |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 45 °C / 113 °F |
| Transport (UN / ADR) | UN 2920 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Analyte Suitability | (alcohols) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Methyl-bis(trifluoroacetamide) used for?
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N-Methyl-bis(trifluoroacetamide) is primarily used as a reagent for introducing the trifluoroacetyl group, especially for the derivatisation of alcohols, facilitating their analysis.
What is the CAS number and chemical formula for N-Methyl-bis(trifluoroacetamide)?
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The CAS number is 685-27-8, and the linear formula is CF<sub>3</sub>CON(CH<sub>3</sub>)COCF<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Methyl-bis(trifluoroacetamide) with a purity of ≥97.0% as determined by GC, designated as 'purum' grade. We do not represent this product as USP, BP, or EP grade.
How should N-Methyl-bis(trifluoroacetamide) be handled safely?
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N-Methyl-bis(trifluoroacetamide) is classified as a Danger with hazards including flammability (H226) and causing severe skin burns and eye damage (H314). Appropriate personal protective equipment, including gloves, eye protection (goggles/face shield), and respiratory protection, must be used. Handle in a well-ventilated area, away from ignition sources.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions professionally packs and ships fine chemicals globally, adhering to all relevant international transport regulations for hazardous materials like UN 2920.
How can I request a sample or quote for N-Methyl-bis(trifluoroacetamide)?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels, providing your specific requirements.
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