N-Methoxy-N-methylacetamide
N-Methoxy-N-methylacetamide (CAS: 78191-00-1) is a chemical compound with the formula CH3CON(OCH3)CH3. This organic molecule, also known as a Weinreb amide derivative, functions as a versatile building block in organic synthesis. Its unique structure allows for controlled reactions, particularly in the formation of ketones and aldehydes, making it valuable in the development of complex organic molecules and pharmaceutical intermediates.
Organic Synthesis Intermediate
N-Methoxy-N-methylacetamide serves as a key intermediate in various organic synthesis pathways. Its reactivity is often exploited for the controlled introduction of acyl groups, facilitating the construction of more complex molecular architectures.
Pharmaceutical Intermediate
This compound is utilized in the synthesis of active pharmaceutical ingredients (APIs) and related molecules. Its application in constructing specific structural motifs is valuable for drug discovery and development programs.
Reagent for Ketone and Aldehyde Synthesis
As a Weinreb amide, N-Methoxy-N-methylacetamide is particularly useful for the synthesis of ketones and aldehydes. It reacts with organometallic reagents to form stable intermediates that resist over-addition, enabling precise product formation.
Building Block in Specialty Chemicals
The compound is employed as a building block for the creation of various specialty chemicals. Its functional group allows for diverse chemical transformations, contributing to the synthesis of fine chemicals and research reagents.
| Molecular weight | 103.12 |
|---|---|
| Linear formula | CH3CON(OCH3)CH3 |
| Assay | 98% |
| Boiling point | 152 °C(lit.) |
| Density | 0.97 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.426(lit.) |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 49 °C / 120.2 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Risk statements (R) | 10 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Methoxy-N-methylacetamide used for?
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N-Methoxy-N-methylacetamide is primarily used as a versatile building block and intermediate in organic synthesis, particularly for the controlled synthesis of ketones and aldehydes, and in the development of pharmaceutical intermediates and specialty chemicals.
What is the CAS number and chemical formula for N-Methoxy-N-methylacetamide?
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The CAS number is 78191-00-1, and the chemical formula is CH3CON(OCH3)CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Methoxy-N-methylacetamide with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should N-Methoxy-N-methylacetamide be handled safely?
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N-Methoxy-N-methylacetamide is a flammable liquid and vapour (H226). Handle with appropriate personal protective equipment, including eyeshields and gloves, in a well-ventilated area, away from ignition sources. Refer to the safety data sheet for detailed handling instructions.
How is N-Methoxy-N-methylacetamide shipped and exported?
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N-Methoxy-N-methylacetamide is classified under UN 1993, Class 3, Packing Group III, indicating it is a flammable liquid. TSS adheres to all relevant regulations for its safe packaging, shipping, and export.
How can I request a sample or quote for N-Methoxy-N-methylacetamide?
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To request a sample or a quote for N-Methoxy-N-methylacetamide, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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