N-Fmoc-ethylenediamine hydrobromide
N-Fmoc-ethylenediamine hydrobromide (CAS: 352351-55-4), with the molecular formula C17H18N2O2 · HBr and a molecular weight of 363.25 g/mol, is a key organic building block. It serves as a valuable bifunctional linker in chemical synthesis. This compound is particularly useful in peptide chemistry and the development of chemical probes, facilitating the introduction of ethylenediamine moieties with amine protection.
- IUPAC
- 9-Fluorenylmethyl N-(2-aminoethyl)carbamate hydrobromide,N-Fmoc-1,2-diaminoethane hydrobromide
Peptide Synthesis
N-Fmoc-ethylenediamine hydrobromide is employed as a protected diamine building block in solid-phase peptide synthesis. The Fmoc protecting group allows for controlled deprotection and subsequent coupling reactions, enabling the construction of complex peptide sequences.
Linker Chemistry
As a bifunctional linker, it can be used to conjugate molecules or modify surfaces. The presence of both a protected amine and a free amine (after deprotection) allows for versatile attachment strategies in drug discovery and materials science.
Chemical Biology
This compound finds application in the synthesis of bioconjugates and probes for studying biological systems. It enables the incorporation of specific functionalities into biomolecules for imaging, diagnostics, or therapeutic applications.
| Molecular weight | 363.25 |
|---|---|
| Empirical formula | C17H18N2O2 · HBr |
| Assay | ≥98.0% (AT) |
| Storage temperature | 2-8°C |
| Melting point | ~165 °C (dec.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Fmoc-ethylenediamine hydrobromide used for?
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N-Fmoc-ethylenediamine hydrobromide is primarily used as a protected bifunctional linker and building block in organic synthesis, particularly in peptide synthesis and chemical biology for creating conjugates and probes.
What is the CAS number and formula for N-Fmoc-ethylenediamine hydrobromide?
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The CAS number is 352351-55-4 and the formula is C17H18N2O2 · HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Fmoc-ethylenediamine hydrobromide with an assay of ≥98.0% (AT). This is a technical/research grade material and is not represented as USP/BP/EP or pharmacopoeia grade.
What are the safety and handling precautions for this compound?
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This compound is classified as a Warning with hazards including skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). When handling, use a dust mask type N95, eyeshields, and gloves. Ensure adequate ventilation.
How is N-Fmoc-ethylenediamine hydrobromide typically stored and shipped?
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It is recommended to store N-Fmoc-ethylenediamine hydrobromide at 2-8°C. TSS ships this chemical product globally, adhering to all relevant transport regulations.
How can I request a quote or sample for N-Fmoc-ethylenediamine hydrobromide?
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Please contact our sales department via the website or by phone to request a quote or a sample of N-Fmoc-ethylenediamine hydrobromide.
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