N-Desmethylclozapine
N-Desmethylclozapine (CAS: 6104-71-8), a chemical compound with the formula C17H17ClN4 and a molecular weight of 312.80 g/mol, is a notable molecule within neuropharmacology and receptor research. As a metabolite of clozapine, it serves as a valuable tool for scientists investigating dopaminergic and serotonergic pathways. Its properties make it useful in studies related to neurotransmission and the mechanisms of action for certain psychiatric medications.
- IUPAC
- 8-Chloro-11-piperazinyl-5H-dibenzo[b,e][1,4]diazepine,Norclozapine,Normethylclozapine
- Synonyms
- NorclozapineNormethylclozapine
Neuroscience Research
N-Desmethylclozapine is utilised in preclinical research to investigate its effects on neurotransmitter systems, particularly dopamine and serotonin receptors. This aids in understanding complex neurological processes and drug mechanisms.
Pharmacological Studies
As a metabolite, it is employed in studies evaluating the metabolic fate and pharmacological activity of parent compounds like clozapine. This research is crucial for drug development and understanding drug interactions.
Biochemical Assays
This compound can be used as a reference standard or tool compound in various biochemical and cellular assays designed to probe receptor binding and signaling pathways.
| Molecular weight | 312.80 |
|---|---|
| Empirical formula | C17H17ClN4 |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/22-36/37/38 |
| Safety statements (S) | 22-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Drug Control | regulated under CDSA - not available from Canada |
|---|---|
| Gene Information | human ... KCNH1(3756) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Desmethylclozapine used for?
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N-Desmethylclozapine is primarily used in scientific research, particularly in neuroscience and pharmacology, to study neurotransmission, receptor interactions, and the metabolic pathways of related drugs.
What is the CAS number and chemical formula for N-Desmethylclozapine?
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The CAS number for N-Desmethylclozapine is 6104-71-8, and its empirical formula is C17H17ClN4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Desmethylclozapine typically as a research-grade chemical. The exact purity/assay is detailed on the Certificate of Analysis for each batch. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling requirements for N-Desmethylclozapine?
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N-Desmethylclozapine is classified with GHS07 symbol and carries a Warning signal word. It has hazard statements including H302 (Harmful if swallowed), H315 (Causes skin irritation), H319 (Causes serious eye irritation), H332 (Harmful if inhaled), and H335 (May cause respiratory irritation). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Handle in a well-ventilated area and avoid dust formation.
Is N-Desmethylclozapine a controlled substance?
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Yes, N-Desmethylclozapine is regulated under the CDSA and is not available for export from Canada.
How can I request a sample or quote for N-Desmethylclozapine?
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To request a sample or a quote for N-Desmethylclozapine, please contact our sales department through the website or via the provided email and phone number. Our team will be happy to assist you.
How is N-Desmethylclozapine packed, shipped, and exported?
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N-Desmethylclozapine is carefully packed according to industry standards to ensure safe transit. As a regulated substance, shipping and export are subject to specific international and national regulations. Please contact us for detailed information regarding your specific region.
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