N-Aminophthalimide
N-Aminophthalimide (CAS: 1875-48-5), with the molecular formula C8H6N2O2 and a molecular weight of 162.15 g/mol, is a key organic building block. This compound is primarily utilised in organic synthesis, serving as a precursor in the preparation of various heterocyclic compounds. It plays a role in reactions such as aziridination and the synthesis of substituted aziridines, making it valuable for complex chemical construction.
- IUPAC
- N,N-Phthaloylhydrazine, unsym.
- Synonyms
- N,N-Phthaloylhydrazine, unsym.

Aziridination Reagent
N-Aminophthalimide is employed as a reagent in the aziridination of chiral N-enoyl sultams, facilitating the formation of complex cyclic structures.
Synthesis of N-Phthalimidoaziridines
This compound serves as a crucial starting material for the synthesis of N-phthalimidoaziridines, which are important intermediates in organic chemistry.
Organic Synthesis Building Block
As a versatile organic building block, N-Aminophthalimide is integral to the construction of more complex molecules, particularly those containing nitrogen heterocycles.
| Molecular weight | 162.15 |
|---|---|
| Empirical formula | C8H6N2O2 |
| Assay | ~90% (HPLC) |
| Storage temperature | 2-8°C |
| Application | N-Aminophthalimide was employed in the aziridination of chiral N-enoyl sultams1. It was also used in the synthesis of n-phthalimidoaziridines2. |
| Melting point | 200-202 °C(lit.) |


Hazard statements
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 36/37/38-42/43 |
| Safety statements (S) | 22-26-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Aminophthalimide used for?
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N-Aminophthalimide is primarily used as a building block in organic synthesis, specifically for reactions such as the aziridination of chiral N-enoyl sultams and the synthesis of N-phthalimidoaziridines.
What is the CAS number and chemical formula for N-Aminophthalimide?
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The CAS number for N-Aminophthalimide is 1875-48-5, and its chemical formula is C8H6N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Aminophthalimide with an assay of approximately 90% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should N-Aminophthalimide be handled safely?
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N-Aminophthalimide is classified as a Danger. Hazards include skin irritation (H315), allergic skin reaction (H317), serious eye irritation (H319), and potential respiratory irritation (H335) and respiratory sensitisation (H334). Use a dust mask type N95 (US), safety eyeshields, face shields, and gloves. Ensure adequate ventilation.
How is N-Aminophthalimide packed and shipped?
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N-Aminophthalimide is typically stored at 2-8°C. Specific packing and shipping details are available upon request, adhering to international export regulations.
How can I request a sample or quote for N-Aminophthalimide?
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To request a sample or quote, please contact our sales department via the website or direct telephone line.
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