N-Allyl-(±)-SKF-38393 hydrobromide
N-Allyl-(±)-SKF-38393 hydrobromide (CAS: 300561-58-4), with the chemical formula C19H21NO2 · HBr and a molecular weight of 376.29 g/mol, is a white to off-white solid. This compound serves as a valuable tool in neurochemical research, particularly for investigating dopaminergic signalling pathways. It has been utilised in studies involving developing mouse neurons and in models of cardiomyocyte injury.
- IUPAC
- (±)-SKF-77434 hydrobromide,(±)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide
- Synonyms
- (±)-SKF-77434 hydrobromide(±)-7,8-Dihydroxy-3-allyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide

Neuroscience Research
N-Allyl-(±)-SKF-38393 hydrobromide is employed in research studies focused on dopaminergic signalling within neuronal systems. Its use aids in understanding the complex mechanisms of neurotransmission and receptor function in the brain.
Cardiomyocyte Injury Studies
This compound has been applied to investigate the effects of dopaminergic signalling in cardiomyocytes subjected to oxidative stress. Such research contributes to understanding cellular responses to injury and potential therapeutic targets.
Dopamine Receptor Modulation
As a dopaminergic agonist, N-Allyl-(±)-SKF-38393 hydrobromide is instrumental in exploring the function and regulation of dopamine receptors, specifically the D1 receptor (DRD1) in various biological contexts.
| Molecular weight | 376.29 |
|---|---|
| Empirical formula | C19H21NO2 · HBr |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | ethanol: soluble3.2 mg/mLDMSO: >50 mg/mLH2O: soluble6.0 mg/mL0.1 M HCl: soluble6.3 mg/mL |
| Storage temperature | 2-8°C |
| Application | N-Allyl-(±)-SKF-38393 hydrobromide was used to study dopaminergic signaling in neurons of developing mice1 and cardiomyocytes injured by oxidants.2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812) |
|---|---|
| Storage Condition | protect from light |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Allyl-(±)-SKF-38393 hydrobromide used for?
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N-Allyl-(±)-SKF-38393 hydrobromide is used in research for studying dopaminergic signalling in neurons and in models of cardiomyocyte injury. It acts as a dopaminergic agonist, particularly relevant for D1 receptor research.
What is the CAS number and chemical formula for N-Allyl-(±)-SKF-38393 hydrobromide?
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The CAS number is 300561-58-4 and the chemical formula is C19H21NO2 · HBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Allyl-(±)-SKF-38393 hydrobromide with a purity of ≥98% (HPLC). This product is intended for research purposes and TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions for N-Allyl-(±)-SKF-38393 hydrobromide?
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When handling N-Allyl-(±)-SKF-38393 hydrobromide, it is essential to wear appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified with WGK Germany 3, indicating a high hazard to water.
How is N-Allyl-(±)-SKF-38393 hydrobromide shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all necessary regulations for safe and compliant shipment worldwide.
How can I request a quote or sample for N-Allyl-(±)-SKF-38393 hydrobromide?
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To request a quote or sample for N-Allyl-(±)-SKF-38393 hydrobromide, please contact our sales team through the TSS website. We are dedicated to serving your research needs.
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