N-Acetylprocainamide
N-Acetylprocainamide (CAS: 32795-44-1) is an organic compound with a molecular weight of 277.36 g/mol. This amide derivative, represented by the linear formula 4-(CH3CONH)C6H4CONHCH2CH2N(C2H5)2, is recognised for its utility in chemical synthesis. It serves as a valuable building block and has been employed in research, such as in studies to establish predictive models for drug clearance.

Research and Development
N-Acetylprocainamide is utilized as a research chemical and an organic building block in synthetic chemistry. Its structural features make it suitable for exploring new molecular entities and reaction pathways.
Pharmacological Studies
The compound has been used in scientific investigations as a model drug. For instance, it played a role in developing quantitative approaches to predict the renal clearances of basic drugs, contributing to a better understanding of pharmacokinetic principles.
Chemical Synthesis Intermediate
As a carbonyl compound and amide, N-Acetylprocainamide functions as an intermediate in various chemical synthesis processes. It can be incorporated into more complex molecular structures for diverse applications.
| Molecular weight | 277.36 |
|---|---|
| Linear formula | 4-(CH3CONH)C6H4CONHCH2CH2N(C2H5)2 |
| Assay | ≥99% |
| Solubility | : soluble1%, clear, colorless to faintly yellow (1N HCl) |
| Application | N-acetylprocainamide (NAPA) was used as a model drug in the study of establishing a quantitative approach to predict the renal clearances of basic drugs using N-1-methylnicotinamide (NMN)1. |
| Melting point | 138-140 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Acetylprocainamide used for?
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N-Acetylprocainamide is used in chemical synthesis and has been employed as a model drug in research, particularly in studies related to predicting drug clearance.
What is the CAS number and formula for N-Acetylprocainamide?
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The CAS number for N-Acetylprocainamide is 32795-44-1, and its linear formula is 4-(CH3CONH)C6H4CONHCH2CH2N(C2H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Acetylprocainamide with an assay of ≥99%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated in the product specifications.
What are the safety and handling considerations for N-Acetylprocainamide?
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N-Acetylprocainamide is classified with a Warning signal word and carries hazard statements H315, H319, and H335, indicating it can cause skin irritation, serious eye irritation, and respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is N-Acetylprocainamide packed, shipped, and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations and exported worldwide.
How can I request a quote or sample for N-Acetylprocainamide?
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To request a quote or sample of N-Acetylprocainamide, please contact our sales team through the website or by calling our dedicated number.
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