N-(3-Aminophenyl)methanesulfonamide
N-(3-Aminophenyl)methanesulfonamide (CAS 37045-73-1), with the molecular formula C7H10N2O2S and a molecular weight of 186.23 g/mol, is a key organic building block. This sulfonamide derivative serves as a crucial reactant in the synthesis of various biologically and pharmacologically active molecules. Its utility lies in its specific chemical structure, enabling its incorporation into complex molecular frameworks for pharmaceutical research and development.
- IUPAC
- 3-N-(Methylsulfonyl)aminoaniline,3-(Methylsulfonylamino)aniline,N-(3-Aminophenyl)methanesulfamide
- Synonyms
- 3-(Methylsulfonylamino)anilineN-(3-Aminophenyl)methanesulfamide3-N-(Methylsulfonyl)aminoaniline

Synthesis of Bioactive Molecules
Serves as a critical reactant in the preparation of molecules with demonstrated biological activity. Its structure is amenable to further functionalization for drug discovery efforts.
Pharmaceutical Intermediate
Acts as a valuable intermediate in the multi-step synthesis of complex pharmaceutical compounds. Enables the introduction of the methanesulfonamide moiety into target structures.
Chemical Synthesis Research
Utilised as a building block in academic and industrial research for exploring novel chemical pathways and creating diverse organic compounds.
| Molecular weight | 186.23 |
|---|---|
| Empirical formula | C7H10N2O2S |
| Application | Reactant for:• Preparation of biologically and pharmacologically active molecules1,2,3,4 |
| Melting point | 117-121 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(3-Aminophenyl)methanesulfonamide used for?
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N-(3-Aminophenyl)methanesulfonamide (CAS 37045-73-1) is primarily used as a reactant for the preparation of biologically and pharmacologically active molecules.
What are the CAS number and molecular formula for N-(3-Aminophenyl)methanesulfonamide?
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The CAS number is 37045-73-1, and the molecular formula is C7H10N2O2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-(3-Aminophenyl)methanesulfonamide typically as a research or technical grade chemical. The exact assay and purity are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should N-(3-Aminophenyl)methanesulfonamide be handled?
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Handling requires appropriate personal protective equipment, including a dust mask (N95 type), eyeshields, and gloves, to mitigate risks of skin, eye, and respiratory irritation (H315, H319, H335). Ensure adequate ventilation.
Can you export N-(3-Aminophenyl)methanesulfonamide?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including N-(3-Aminophenyl)methanesulfonamide.
How can I request a sample or quote for N-(3-Aminophenyl)methanesulfonamide?
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To request a sample or quote, please contact our sales team through the provided contact channels on the Tech Serve Solutions website.
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