4-Bromo-1,2-difluorobenzene
4-Bromo-1,2-difluorobenzene (CAS 348-61-8) is a halogenated aromatic compound with the molecular formula BrC6H3F2 and a molecular weight of 192.99 g/mol. This fluorinated building block is primarily used in chemical synthesis. Available at a purity of 98%, it serves as a valuable intermediate for the development of more complex organic molecules, particularly within pharmaceutical research and materials science. Tech Serve Solutions supplies this reagent for laboratory and industrial applications.
- Synonyms
- BrC6H3F2

Intermediate in Organic Synthesis
4-Bromo-1,2-difluorobenzene functions as a key building block in the synthesis of various organic compounds. Its reactivity allows for further functionalization, enabling the creation of novel molecular structures.
Pharmaceutical Research
This compound has been utilised in the preparation of complex molecules, such as 4-benzyl-2-(3,4-difluorophenyl)-2-hydroxy-morpholine. It contributes to the development pipeline for new therapeutic agents.
Materials Science Applications
As a fluorinated aryl compound, it can be incorporated into polymers or other advanced materials, potentially modifying their electronic or physical properties. Its specific applications in this field are diverse and under ongoing research.
| Molecular weight | 192.99 |
|---|---|
| Linear formula | BrC6H3F2 |
| Assay | 98% |
| Boiling point | 150-151 °C(lit.) |
| Density | 1.707 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.505(lit.) |
| Application | 4-Bromo-1,2-difluorobenzene has been used in the preparation of 4-benzyl-2-(3,4-difluorophenyl)-2-hydroxy-morpholine1. |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 33 °C / 91.4 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Bromo-1,2-difluorobenzene used for?
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4-Bromo-1,2-difluorobenzene is used as a building block in organic synthesis and has applications in pharmaceutical research, including the preparation of complex molecules like morpholine derivatives.
What are the CAS number and formula for 4-Bromo-1,2-difluorobenzene?
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The CAS number is 348-61-8, and its linear formula is BrC6H3F2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Bromo-1,2-difluorobenzene with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 4-Bromo-1,2-difluorobenzene be handled?
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4-Bromo-1,2-difluorobenzene is a flammable liquid and vapour (H226) and causes skin (H315), eye (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, in a well-ventilated area, away from ignition sources.
Is 4-Bromo-1,2-difluorobenzene exported by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Bromo-1,2-difluorobenzene.
How can I request a quote or sample?
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Please contact our sales team via the website or direct inquiry channels to request a quote or a sample of 4-Bromo-1,2-difluorobenzene.
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