N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine (CAS 58970-76-6) is a complex organic compound with a molecular weight of 308.37 g/mol. This chemical is primarily recognised as an enzyme inhibitor, specifically targeting aminopeptidases. Its precise structure and inhibitory properties make it a valuable tool in biochemical research and chemical biology for studying enzyme mechanisms and developing new therapeutic agents.
- IUPAC
- ([2S,3R]-3-Amino-2-hydroxy-4-phenylbutanoyl)-L-leucine
- Synonyms
- (2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl-L-leucine(CH3)2CHCH2CH[NHCOCH(OH)CH(NH2)CH2C6H5]CO2H
![N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine ((CH3)2CHCH2CH[NHCOCH(OH)CH(NH2)CH2C6H5]CO2H) — chemical structure, CAS 58970-76-6; Life Science, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F58970-76-6.png&w=3840&q=75)
Enzyme Inhibition Studies
This compound serves as a specific inhibitor for enzymes such as Aminopeptidase N. Researchers utilise it to elucidate enzyme kinetics, understand biological pathways, and as a reference standard in biochemical assays.
Chemical Biology Research
As a bioactive small molecule, it is employed in chemical biology to probe cellular processes and enzyme functions. Its well-defined stereochemistry and inhibitory action aid in the development of targeted molecular probes.
Peptide Chemistry and Synthesis
This molecule is a derivative of leucine and contains modified amino acid components. It can be a useful building block or reference compound in complex peptide synthesis and the study of unnatural amino acids.
| Molecular weight | 308.37 |
|---|---|
| Linear formula | (CH3)2CHCH2CH[NHCOCH(OH)CH(NH2)CH2C6H5]CO2H |
| Assay | 97% |
| Optical activity | [α]20/D −11°, c = 1 in 1 M NaOH |
| Melting point | 245 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ANPEP(290), DPP4(1803)mouse ... Rnpep(215615)rat ... Mme(24590) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine used for?
+
This compound is primarily used as an enzyme inhibitor, particularly for aminopeptidases, in biochemical research and chemical biology studies. It is also relevant in peptide chemistry and the synthesis of unnatural amino acid derivatives.
What are the CAS number and formula for this compound?
+
The CAS number is 58970-76-6. The linear formula is (CH3)2CHCH2CH[NHCOCH(OH)CH(NH2)CH2C6H5]CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine with an assay of 97%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations?
+
Safety precautions include using eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified under WGK Germany 3, indicating it is hazardous to water.
How is this chemical packed and shipped?
+
This product is carefully packed to ensure stability during transit and is available for export globally by Tech Serve Solutions, a trusted supplier since 1998.
How can I request a sample or quote?
+
To request a sample or a quote for N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine, please contact our sales team through our website or by phone.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis