MTS-4-Fluorescein
MTS-4-Fluorescein (CAS: 351330-42-2), with the empirical formula C24H19NO8S2 and a molecular weight of 513.54 g/mol, is a biochemical reagent used for labeling thiols. Its primary application involves targeting cysteine side chains in proteins. This compound is supplied by Tech Serve Solutions for research and development purposes.
- IUPAC
- 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl methanthiosulfonate

Thiol Labeling in Proteins
MTS-4-Fluorescein is utilised to specifically label thiol groups, such as those found in cysteine residues within protein structures. This enables researchers to track or modify proteins for various biochemical studies.
Fluorescent Probing
The fluorescein moiety allows for fluorescent detection of labeled molecules, with excitation at 492 nm and emission at 516 nm. This makes it valuable for applications requiring fluorescent visualisation in biological systems.
Bioconjugation Reagent
As a methanethiosulfonate derivative, MTS-4-Fluorescein is suitable for coupling reactions with thiols. This facilitates the creation of bioconjugates for research in molecular biology and chemical biology.
| Molecular weight | 513.54 |
|---|---|
| Empirical formula | C24H19NO8S2 |
| Assay | ≥90% (TLC) |
| Storage temperature | −20°C |
| Application | 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl methanethiosulfonate (MTS-4-Fluorescein) is used to label thiols such as the cysteine side chains in proteins. |
| Suitability | corresponds for coupling to thiols |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Fluorescence | λex 492 nm; λem 516 nm in 0.1 M phosphate pH 7.0 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is MTS-4-Fluorescein used for?
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MTS-4-Fluorescein is used to label thiols, particularly the cysteine side chains in proteins, and for fluorescent probing in biochemical studies.
What are the CAS number and molecular formula for MTS-4-Fluorescein?
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The CAS number for MTS-4-Fluorescein is 351330-42-2, and its empirical formula is C24H19NO8S2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies MTS-4-Fluorescein with an assay of ≥90% (TLC). This product is suitable for coupling to thiols and is supplied for research purposes. TSS does not represent it as USP, BP, or EP grade.
How should MTS-4-Fluorescein be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or P1 (EN143) respirator filter. The recommended storage temperature is -20°C.
Is MTS-4-Fluorescein a controlled substance?
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The provided data does not indicate that MTS-4-Fluorescein is a controlled substance.
How is MTS-4-Fluorescein shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, capable of shipping and exporting MTS-4-Fluorescein worldwide.
How can I request a sample or quote for MTS-4-Fluorescein?
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Please contact Tech Serve Solutions directly through our website or sales department to request a sample or a quotation for MTS-4-Fluorescein.
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