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MK-912 hydrochloride hydrate

CAS 111466-41-2 (free base)C20H25N3O2 · xHCl · yH2OCell Biology

MK-912 hydrochloride hydrate (CAS: 111466-41-2) is a research chemical with the empirical formula C20H25N3O2 · xHCl · yH2O and a molecular weight of 339.43 (anhydrous free base basis). It is supplied as a white to beige powder. This compound is utilized in scientific research, primarily within the fields of neuroscience and cell biology, for its properties as an adrenergic antagonist. Tech Serve Solutions offers this compound for laboratory and research purposes.

IUPAC
(2S-trans)-1,3,4,5′,6,6′,7,12b-Octahydro-1′,3′-dimethyl-spiro[2H-benzofuro[2,3-a]quinolizine-2,4′(1’H)-pyrimidin]-2′(3’H)-one hydrochloride hydrate,L-657,743
Synonyms
L-657,743
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MK-912 hydrochloride hydrate (C20H25N3O2 · xHCl · yH2O) — chemical structure, CAS 111466-41-2 (free base); Life Science, fine chemical supplied by Tech Serve Solutions
AdrenergicsAntagonistsBioactive Small MoleculesCell BiologyMerckNeuroscienceNeurotransmissionNeurotransmitters More...
01 /Applications

Neuroscience Research

MK-912 hydrochloride hydrate is employed in neuroscience research to investigate adrenergic receptor pathways and neurotransmission. Its antagonist properties make it a valuable tool for studying the role of these receptors in cellular signalling.

Cell Biology Studies

This compound serves as a bioactive small molecule in cell biology, aiding in the exploration of cellular functions and signalling cascades. Its application extends to understanding Adrenoceptor Beta 2 (ADRB2) mediated processes.

Drug Discovery and Development

As an approved therapeutic/drug candidate, MK-912 hydrochloride hydrate may be used in preclinical research phases for potential therapeutic agents targeting the adrenergic system. Researchers utilise it to understand drug interactions and efficacy.

02 /Properties
Molecular weight339.43 (anhydrous free base basis)
Empirical formulaC20H25N3O2 · xHCl · yH2O
Assay≥98% (HPLC)
Formpowder
Colourwhite to beige
SolubilityH2O: soluble16 mg/mL
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
05 /Additional specifications
Gene Informationhuman ... ADRB2(154)
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is MK-912 hydrochloride hydrate used for?

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MK-912 hydrochloride hydrate is used in scientific research, primarily for neuroscience and cell biology studies. It functions as an adrenergic antagonist and is relevant for investigating neurotransmission and cellular signalling pathways.

What is the CAS number and formula for MK-912 hydrochloride hydrate?

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The CAS number for the free base is 111466-41-2. The empirical formula is C20H25N3O2 · xHCl · yH2O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies MK-912 hydrochloride hydrate with an assay of ≥98% (HPLC). This product is intended for research and laboratory use; TSS does not represent it as USP, BP, or EP grade.

How should MK-912 hydrochloride hydrate be handled?

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Handling MK-912 hydrochloride hydrate requires appropriate safety measures. Personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany rating of 3, indicating a high hazard.

How is MK-912 hydrochloride hydrate shipped?

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MK-912 hydrochloride hydrate is packaged and shipped as a white to beige powder. As a global supplier and exporter, Tech Serve Solutions adheres to all relevant regulations for chemical transport.

How can I request a sample or quote for MK-912 hydrochloride hydrate?

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To request a sample or quote for MK-912 hydrochloride hydrate, please contact the Tech Serve Solutions sales department through our website or by phone. Provide the product name and CAS number for prompt service.

Need MK-912 hydrochloride hydrate in a specific grade or volume?