MK-0343
MK-0343 (CAS 233275-76-8) is a chemical compound with the molecular formula C19H17F2N7O and a molecular weight of 397.38. It is supplied as a white to beige powder. This compound functions as an agonist, primarily utilised in research settings for cell biology, cell signalling, and neuroscience studies, particularly those involving GABAergic pathways and neurotransmission.
- IUPAC
- 7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine,MRK-409
- Synonyms
- 7-Cyclobutyl-3-(2,6-difluorophenyl)-6-[(1-methyl-1H-1,2,4-triazol-5-yl)methoxy]-1,2,4-triazolo[4,3-b]pyridazine,MRK-409

Neuroscience Research
MK-0343 is employed in neuroscience research to investigate the mechanisms of neurotransmission and the function of GABAergic systems. Its agonist properties are valuable for studying cellular responses in the nervous system.
Cell Biology Studies
This compound serves as a tool in cell biology research, enabling scientists to explore cellular signalling pathways. Its specific interactions can help elucidate complex biological processes at the cellular level.
GABAergic System Investigation
As a GABAergic agent, MK-0343 is utilised to examine the function and regulation of the gamma-aminobutyric acid (GABA) system, a key inhibitory neurotransmitter system in the central nervous system.
| Molecular weight | 397.38 |
|---|---|
| Empirical formula | C19H17F2N7O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white to beige |
| Solubility | DMSO: soluble10 mg/mL, clear |
| Storage temperature | 2-8°C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is MK-0343 used for?
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MK-0343 is an agonist used in neuroscience, cell biology, and cell signalling research, particularly for investigating GABAergic pathways and neurotransmission.
What is the CAS number and molecular formula for MK-0343?
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The CAS number for MK-0343 is 233275-76-8, and its molecular formula is C19H17F2N7O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies MK-0343 with an assay of ≥98% (HPLC). This product is intended for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.
How should MK-0343 be handled and stored?
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MK-0343 is supplied as a powder and should be stored at 2-8°C. Handle with appropriate laboratory precautions to avoid exposure. Consult the Safety Data Sheet for comprehensive hazard information.
How is MK-0343 packed, shipped, and exported?
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MK-0343 is carefully packed to ensure stability during transit. Tech Serve Solutions is experienced in exporting fine chemicals globally, adhering to all necessary regulations.
How can I request a sample or quote for MK-0343?
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To request a sample or a quotation for MK-0343, please contact our sales team through the website or by direct enquiry, providing your contact details and required quantity.
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