Microcystin YR from Microcystis aeruginosa
Microcystin YR (CAS: 101064-48-6), with the molecular formula C52H72N10O13 and a molecular weight of 1045.19, is a potent cyclic peptide toxin produced by cyanobacteria, primarily from the genus Microcystis. This compound is a well-characterised hepatotoxin and a potent inhibitor of protein phosphatases 1 and 2A. Its primary applications lie in biochemical research, particularly in the study of cell signalling pathways and toxicity mechanisms.
Research Tool for Cell Signalling Studies
Microcystin YR serves as a valuable research tool for investigating the intricate pathways of cell signalling, specifically focusing on the roles of protein phosphatases. It aids in understanding cellular responses to environmental stressors and disease mechanisms.
Toxicology and Environmental Health Research
This toxin is extensively used in toxicological studies to understand the mechanisms of cyanobacterial poisoning and its impact on aquatic ecosystems and human health. It helps in developing detection methods and assessing water quality.
Biochemical Assay Development
Due to its specific inhibitory action on protein phosphatases, Microcystin YR is utilised in the development and validation of biochemical assays designed to screen for phosphatase activity or inhibitors.
| Molecular weight | 1045.19 |
|---|---|
| Empirical formula | C52H72N10O13 |
| Form | white powder |
| Solubility | methanol: soluble2 mg/mL ((further dilute to 10% (v/v) methanol))DMSO: solubleethanol: soluble |
| Storage temperature | −20°C |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H330Fatal if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811PIH 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28-36/37/38-43 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Microcystin YR used for?
+
Microcystin YR is primarily used as a research tool in toxicology, cell signalling studies, and biochemical assay development due to its potent inhibitory effects on protein phosphatases.
What are the CAS number and formula for Microcystin YR?
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The CAS number for Microcystin YR is 101064-48-6, and its molecular formula is C52H72N10O13.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Microcystin YR as a white powder. Purity information and specific grades are available upon request; TSS does not represent this product as USP, BP, or EP grade.
How should Microcystin YR be handled safely?
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Microcystin YR is highly toxic and requires stringent safety precautions. Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator. Ensure good ventilation and avoid inhalation, ingestion, and skin contact due to hazards H300, H310, H330, H315, H317, and H319.
How is Microcystin YR packed and shipped?
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Microcystin YR is typically stored at -20°C. TSS is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a sample or quote for Microcystin YR?
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To request a sample or quote for Microcystin YR, please contact our sales department through the website or by telephone, providing your specific requirements.
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