Mibefradil dihydrochloride hydrate
Mibefradil dihydrochloride hydrate (CAS: 116666-63-8) is a calcium channel modulator with the empirical formula C29H38FN3O3 · 2HCl · xH2O and a molecular weight of 568.55 g/mol (anhydrous basis). Supplied by Tech Serve Solutions as a white powder, this compound is primarily utilised in research settings for its role in modulating voltage-gated ion channels. Its solubility in water makes it a convenient reagent for various in vitro biological studies.
- IUPAC
- (1S,2S)-2-[2[[3-(2-Benzimidazolyl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate dihydrochloride hydrate,Ro 40-5967 hydrate
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Research in Cardiovascular Physiology
Mibefradil dihydrochloride hydrate serves as a valuable tool for researchers investigating the function of calcium channels in cardiovascular systems. Its specific modulatory effects can be studied to understand cardiac muscle contractility and vascular tone.
Neuroscience and Cell Signaling Studies
This compound is employed in research focused on cell signaling pathways and neuroscience. It can be used to explore the role of specific ion channels in neuronal function and intercellular communication.
Drug Candidate and Bioactive Molecule Research
As an approved therapeutic/drug candidate, mibefradil dihydrochloride hydrate is a significant subject in pharmaceutical research. It is used to study its biological activity and potential therapeutic applications.
| Molecular weight | 568.55 (anhydrous basis) |
|---|---|
| Empirical formula | C29H38FN3O3 · 2HCl · xH2O |
| Assay | ≥98% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble >20 mg/mLabsolute ethanol: insoluble |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Mibefradil dihydrochloride hydrate used for?
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Mibefradil dihydrochloride hydrate is primarily used in research for its properties as a calcium channel modulator, particularly in studies related to cardiovascular physiology, neuroscience, and cell signaling. It is also recognised as an approved therapeutic/drug candidate for further research.
What are the CAS number and formula for Mibefradil dihydrochloride hydrate?
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The CAS number for the anhydrous form is 116666-63-8. The empirical formula is C29H38FN3O3 · 2HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Mibefradil dihydrochloride hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
What are the safety precautions for handling Mibefradil dihydrochloride hydrate?
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Mibefradil dihydrochloride hydrate is classified with GHS07 symbol and a 'Warning' signal word, bearing hazard statement H302 (Harmful if swallowed). Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. Always consult the Safety Data Sheet before handling.
Is Mibefradil dihydrochloride hydrate shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Mibefradil dihydrochloride hydrate, serving customers worldwide.
How can I request a sample or quote?
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To request a sample or a quote for Mibefradil dihydrochloride hydrate, please contact our sales department through the website or by phone.
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