3-(3-Hydroxyphenyl)benzonitrile
3-(3-Hydroxyphenyl)benzonitrile (CAS: 154848-43-8; Formula: C13H9NO; MW: 195.22) is a notable organic building block. This compound, featuring both a nitrile and a hydroxyl group on a biphenyl core, serves as a versatile intermediate in chemical synthesis. It is particularly valuable in the development of advanced materials and complex organic molecules. Available at 97% purity, it is supplied by Tech Serve Solutions for research and industrial applications.
- IUPAC
- 3′-Hydroxy-[1,1′−biphenyl]-3-carbonitrile,3′-Hydroxybiphenyl-3-carbonitrile
- Synonyms
- 3′-Hydroxy-[1,1′−biphenyl]-3-carbonitrile3′-Hydroxybiphenyl-3-carbonitrile

Chemical Synthesis Intermediate
Utilised as a key building block in multi-step organic synthesis pathways. Its functional groups allow for diverse derivatisation, enabling the construction of complex molecular architectures for research and development.
Pharmaceutical Research
Serves as a precursor or intermediate in the synthesis of potential pharmaceutical agents. The biphenylnitrile scaffold is present in various biologically active molecules, making it relevant for drug discovery efforts.
Materials Science
The rigid biphenyl structure and reactive nitrile group make it a candidate for incorporation into functional materials, such as liquid crystals or polymers, requiring specific electronic or structural properties.
| Molecular weight | 195.22 |
|---|---|
| Empirical formula | C13H9NO |
| Assay | 97% |
| Melting point | 105-109 °C(lit.) |



Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H318Causes serious eye damage
- H332Harmful if inhaled
- H411Toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 20/21/22-41-51/53 |
| Safety statements (S) | 26-36/37/39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(3-Hydroxyphenyl)benzonitrile used for?
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3-(3-Hydroxyphenyl)benzonitrile is primarily used as a building block in chemical synthesis, particularly for pharmaceutical research and potentially in materials science applications.
What is the CAS number and formula for 3-(3-Hydroxyphenyl)benzonitrile?
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The CAS number is 154848-43-8 and the empirical formula is C13H9NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(3-Hydroxyphenyl)benzonitrile with a minimum assay of 97%. This product is intended for research and industrial use; TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades.
How should 3-(3-Hydroxyphenyl)benzonitrile be handled safely?
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3-(3-Hydroxyphenyl)benzonitrile is classified as Danger. It is harmful if swallowed, in contact with skin, or if inhaled, and causes serious eye damage (H302, H312, H332, H318). It is also toxic to aquatic life with long-lasting effects (H411). Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Avoid release to the environment. Refer to the Safety Data Sheet for full handling and emergency procedures.
Is 3-(3-Hydroxyphenyl)benzonitrile a controlled substance?
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The provided data does not indicate that 3-(3-Hydroxyphenyl)benzonitrile is a controlled substance.
How is 3-(3-Hydroxyphenyl)benzonitrile packed and shipped?
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3-(3-Hydroxyphenyl)benzonitrile is shipped as UN 3077, Environmentally hazardous substance, solid, n.o.s. (contains 3-(3-Hydroxyphenyl)benzonitrile), 9, III. Packaging adheres to international regulations for transport. Tech Serve Solutions exports globally.
How can I request a quote or sample for 3-(3-Hydroxyphenyl)benzonitrile?
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To request a quote or sample for 3-(3-Hydroxyphenyl)benzonitrile, please contact our sales team through the TSS website or via the provided contact details, specifying the product name and CAS number.
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