α,β-Methyleneguanosine 5′-diphosphate sodium salt
α,β-Methyleneguanosine 5′-diphosphate sodium salt (CAS 161308-39-0) is a nucleotide analog with the empirical formula C11H17N5O10P2 · xNa+. This compound serves as a valuable tool in biochemical research, particularly for studying protein-nucleotide interactions and cellular processes. Its applications include investigating tubulin self-association and bacterial division mechanisms.
- IUPAC
- GMPCP,GPCP
- Synonyms
- GMPCP,GPCP
Tubulin Self-Association Studies
Used as a GDP methylene analog to investigate the mechanisms behind vinblastine-induced self-association of tubulin, a key component of the cytoskeleton.
Bacterial Cytokinesis Research
Serves as an alternative to calcium ions in promoting the formation of helical tubes, facilitating the study of bacterial division via cytokinetic ring (Z-ring) assembly.
Nucleotide Analog Research
Employed in comparative studies with similar nucleotide analogs, such as GMPCPP, to understand hydrolysis rates and structural implications.
| Empirical formula | C11H17N5O10P2 · xNa+ |
|---|---|
| Assay | ≥98% |
| Storage temperature | −20°C |
| Application | α,β-Methyleneguanosine 5′-diphosphate (GPCP; GMPCP) is a GDP methylene analog used to study vinblastine-induced self-association of tubulin. GMPCP is used as an alternative to calcium to produce helical tubes that support bacterial division via assembly of cytokinetic ring structures, Z-rings. GMPCP may be used in comparison with the more slowly hydrolyzed analog guanylyl-(α,β)-methylene-diphosphonate (GMPCPP). |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α,β-Methyleneguanosine 5′-diphosphate sodium salt used for?
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This compound is used in biochemical research to study tubulin self-association and bacterial division mechanisms. It acts as a GDP methylene analog and can be used to produce helical tubes that support bacterial division.
What is the CAS number and formula for this compound?
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The CAS number is 161308-39-0, and the empirical formula is C11H17N5O10P2 · xNa+.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies α,β-Methyleneguanosine 5′-diphosphate sodium salt with a purity of ≥98%. We do not represent this product as USP, BP, or EP grade.
How should α,β-Methyleneguanosine 5′-diphosphate sodium salt be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 or equivalent), eyeshields, and gloves. Ensure good ventilation and avoid breathing dust. In case of contact, follow standard safety procedures as indicated by the hazard statements H315, H319, and H335.
Is this product available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and reagents, including α,β-Methyleneguanosine 5′-diphosphate sodium salt.
How can I request a sample or quote?
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Please contact our sales team directly via phone or email to request a sample or a quotation for α,β-Methyleneguanosine 5′-diphosphate sodium salt.
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