Methyl (S)-(+)-2-pyrrolidone-5-carboxylate
Methyl (S)-(+)-2-pyrrolidone-5-carboxylate (CAS: 4931-66-2, Formula: C6H9NO3, MW: 143.14) is a valuable chiral building block employed in asymmetric synthesis and chemical research. This heterocyclic compound, also known as Methyl L-pyroglutamate, is key in constructing complex molecules where stereochemistry is critical. Its precise structure and properties make it a sought-after reagent for advanced organic synthesis pathways.
- IUPAC
- Methyl L-pyroglutamate
- Synonyms
- Methyl L-pyroglutamate
Asymmetric Synthesis
Utilised as a chiral precursor in the stereoselective synthesis of complex organic molecules, pharmaceuticals, and natural products. Its pyrrolidine core with a defined stereocenter allows for controlled introduction of chirality.
Pharmaceutical Intermediate
Serves as a key building block in the development of various active pharmaceutical ingredients (APIs) where specific stereoisomers are required for therapeutic efficacy and safety.
Chiral Building Block
A versatile synthon for creating novel heterocyclic compounds and chiral ligands, facilitating advancements in medicinal chemistry and materials science.
Chemical Synthesis Research
Employed in academic and industrial research settings for exploring new synthetic methodologies and developing novel chemical entities.
| Molecular weight | 143.14 |
|---|---|
| Empirical formula | C6H9NO3 |
| Assay | 97% |
| Boiling point | 90 °C/0.3 mmHg(lit.) |
| Density | 1.226 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.486(lit.) |
| Optical activity | [α]20/D +10.5°, c = 1 in ethanol |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl (S)-(+)-2-pyrrolidone-5-carboxylate used for?
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Methyl (S)-(+)-2-pyrrolidone-5-carboxylate is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in chemical research and pharmaceutical development.
What are the CAS number and formula for Methyl (S)-(+)-2-pyrrolidone-5-carboxylate?
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The CAS number is 4931-66-2, and the empirical formula is C6H9NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl (S)-(+)-2-pyrrolidone-5-carboxylate with an assay of 97%. It is not classified as USP, BP, or EP grade.
How should Methyl (S)-(+)-2-pyrrolidone-5-carboxylate be handled safely?
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Handle with care. This compound may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Use appropriate personal protective equipment, including eyeshields and gloves, and ensure adequate ventilation. Avoid breathing vapours. For detailed guidance, consult the safety data sheet.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Methyl (S)-(+)-2-pyrrolidone-5-carboxylate.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or call our sales department, providing the product name and CAS number (4931-66-2).
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