Methyl isothiocyanate
Methyl isothiocyanate (CAS 556-61-6), with the molecular formula CH3NCS and a molecular weight of 73.12 g/mol, is a chemical compound recognised for its role as an active ingredient in pesticides like Metam. It is also employed in chemical synthesis and various research applications, including studies in cell biology and nutrition research. Its properties make it a valuable reagent in organic chemistry.

Pesticide Research
Methyl isothiocyanate has been utilized in scientific studies to investigate the impact of pesticides on environmental systems, such as its effect on microbial communities in riverine ecosystems.
Chemical Synthesis
As an organic building block, methyl isothiocyanate serves as a versatile intermediate in the synthesis of more complex organic molecules within research and development laboratories.
Cell Biology Studies
This compound finds application in cell biology research, contributing to investigations into cellular processes and biological mechanisms.
Nutrition Research
Methyl isothiocyanate is used in nutrition research, aiding in the exploration of biochemical pathways and dietary component effects.
| Molecular weight | 73.12 |
|---|---|
| Linear formula | CH3NCS |
| Assay | 97% |
| Boiling point | 117-118 °C(lit.) |
| Density | 1.069 g/cm3 at 25 °C(lit.) |
| Solubility | H2O: slightly soluble |
| Vapour pressure | 21 mmHg (20 °C) |
| Melting point | 30-34 °C(lit.) |
| Application | Methyl isothiocyanate was used to study the effect of pesticide Metam (methyl isothiocyanate is its active ingredient) in the streamside microbial communities of the upper Sacramento river1. |



Hazard statements
- H301Toxic if swallowed
- H310Fatal in contact with skin
- H314Causes severe skin burns and eye damage
- H317May cause an allergic skin reaction
- H330Fatal if inhaled
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
- P302IF ON SKIN
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 30 °C / 86 °F |
| Transport (UN / ADR) | UN 2477 3(6.1) / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 23/25-34-43-50/53 |
| Safety statements (S) | 36/37-38-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl Isothiocyanate used for?
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Methyl Isothiocyanate (CAS 556-61-6) is used in pesticide research, chemical synthesis, cell biology studies, and nutrition research. It is also known as the active ingredient in pesticides like Metam.
What is the CAS number and formula for Methyl Isothiocyanate?
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The CAS number for Methyl Isothiocyanate is 556-61-6, and its chemical formula is CH3NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl Isothiocyanate with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product documentation. It is typically supplied for research and technical use.
How should Methyl Isothiocyanate be handled safely?
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Methyl Isothiocyanate is a dangerous substance requiring strict safety protocols. It is acutely toxic, corrosive, and a sensitiser. Handling requires appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection (e.g., full-face particle respirator type N100 or equivalent). Always consult the Safety Data Sheet (SDS) before use.
How is Methyl Isothiocyanate packed, shipped, and exported?
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Methyl Isothiocyanate is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions exports this chemical globally, ensuring compliance with all relevant transport and customs requirements.
How can I request a sample or quote for Methyl Isothiocyanate?
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To request a sample or a quote for Methyl Isothiocyanate, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
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