Methyl benzo[b]thiophene-2-carboxylate
Methyl benzo[b]thiophene-2-carboxylate (CAS 22913-24-2) is the methyl ester of benzo[b]thiophene-2-carboxylic acid, with molecular formula C10H8O2S and a molar mass of 192.23 g/mol. Supplied as a crystalline solid (melting point 70-74 degC), it is a versatile heterocyclic building block. The reactive ester and benzothiophene scaffold make it a useful intermediate in chemical synthesis, medicinal chemistry research and the preparation of more elaborate benzothiophene derivatives.
- IUPAC
- Benzo[b]thiophene-2-carboxylic acid methyl ester,Methyl thianaphthene-2-carboxylate
- Synonyms
- Methyl benzo[b]thiophene-2-carboxylateBenzo[b]thiophene-2-carboxylic acid methyl esterMethyl thianaphthene-2-carboxylateMethyl 1-benzothiophene-2-carboxylateMethyl benzothiophene-2-carboxylate
![Methyl benzo[b]thiophene-2-carboxylate (C10H8O2S) — chemical structure, CAS 22913-24-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F22913-24-2.png&w=3840&q=75)
Heterocyclic building block
Serves as a benzo[b]thiophene scaffold for the assembly of more complex heterocyclic molecules. The fused thiophene-benzene ring system is a recurring motif in fine-chemical and pharmaceutical research synthesis.
Pharmaceutical intermediate research
Used in medicinal chemistry programmes as a precursor to functionalised benzothiophene derivatives. It supports exploratory and structure-activity work where the benzothiophene core is required.
Ester-directed transformations
The methyl carboxylate offers a convenient handle for hydrolysis, transesterification, amidation and reduction. This allows the 2-position to be elaborated into acids, amides, alcohols and related groups.
Functionalisation of the benzothiophene ring
Provides a starting point for electrophilic substitution, halogenation and cross-coupling chemistry on the aromatic system, enabling access to substituted benzothiophene libraries.
Laboratory reagent and reference material
Employed as a research reagent and characterised intermediate in synthetic and analytical laboratories where a defined benzothiophene-2-carboxylate is needed.
| Molecular weight | 192.23 |
|---|---|
| Empirical formula | C10H8O2S |
| Assay | 97% |
| Melting point | 70-74 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl benzo[b]thiophene-2-carboxylate used for?
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It is used mainly as a heterocyclic building block and synthetic intermediate. The benzothiophene core and reactive methyl ester make it valuable for preparing functionalised benzothiophene derivatives in chemical synthesis and medicinal chemistry research.
What is the CAS number and molecular formula of Methyl benzo[b]thiophene-2-carboxylate?
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The CAS number is 22913-24-2 and the molecular formula is C10H8O2S, corresponding to a molecular weight of 192.23 g/mol. Its MDL number is MFCD00067791.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this material at a typical assay of 97% as a research and technical grade benzothiophene building block. We do not represent it as a USP, BP or EP pharmacopoeia grade. A certificate of analysis can be provided with each batch on request.
What are the safety and handling precautions for this compound?
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It carries GHS07 with the signal word Warning. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust generation, and follow the precautionary advice P261 and P305+P351+P338. It is rated WGK 3 in Germany, so releases to water must be prevented.
Is Methyl benzo[b]thiophene-2-carboxylate a controlled or scheduled substance?
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Based on the supplied data, this compound is not indicated as a controlled or scheduled substance. Customers should nonetheless confirm the import, handling and regulatory requirements applicable in their own jurisdiction.
How is Methyl benzo[b]thiophene-2-carboxylate packed, shipped and exported?
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It is supplied as a solid in securely sealed containers sized from research quantities to larger commercial volumes, with packaging suited to a fine chemical. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant labelling, documentation and global shipping in line with applicable transport regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and a quotation. Samples and a certificate of analysis can be provided to support your evaluation.
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