Methyl acetimidate hydrochloride
Methyl acetimidate hydrochloride (CAS: 14777-27-6; Formula: CH3C(=NH)OCH3 · HCl; Molar Mass: 109.55 g/mol) is a useful organic compound with a primary application in pre-crystallization chemical modification of lysine residues. It serves as a valuable building block in chemical synthesis, particularly within nitrogen compound research and development. Supplied by Tech Serve Solutions, this reagent is characterised by its hydrochloride salt form, ensuring stability for research applications.

Chemical Modification of Lysine Residues
Methyl acetimidate hydrochloride is employed in the specific chemical modification of lysine residues within proteins. This process is often used in pre-crystallization studies to alter the properties of the protein for crystallographic analysis.
Organic Synthesis Building Block
As an organic building block, this compound facilitates the synthesis of more complex molecules. Its structure, featuring an imidate group, makes it suitable for various organic transformations in research and development settings.
Nitrogen Compound Research
This reagent is relevant in the study and synthesis of nitrogen-containing organic compounds. Its properties lend themselves to exploring new reaction pathways and developing novel chemical entities.
| Molecular weight | 109.55 |
|---|---|
| Linear formula | CH3C(=NH)OCH3 · HCl |
| Storage temperature | 2-8°C |
| Application | Methyl acetimidate hydrochloride has been used in pre-crystallization chemical modification of lysine residues1. |
| Melting point | 105 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl acetimidate hydrochloride used for?
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Methyl acetimidate hydrochloride (CAS: 14777-27-6) is primarily used for the pre-crystallization chemical modification of lysine residues in research and development, and as a building block in organic synthesis.
What is the CAS number and molecular formula for Methyl acetimidate hydrochloride?
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The CAS number is 14777-27-6, and the molecular formula is CH3C(=NH)OCH3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl acetimidate hydrochloride. The specific assay and grade are detailed in the product specifications. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product data.
How should Methyl acetimidate hydrochloride be handled safely?
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Methyl acetimidate hydrochloride is a warning substance that can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
How is Methyl acetimidate hydrochloride packed, shipped, and exported?
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Products are packed according to industry standards to ensure safe transit. Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals and laboratory reagents. Specific shipping and export details can be provided upon request.
How can I request a sample or quote for Methyl acetimidate hydrochloride?
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To request a sample or a quote for Methyl acetimidate hydrochloride, please contact our sales department via the website or by phone. Please reference the product name and CAS number (14777-27-6).
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