Methyl 5-methoxypyridine-3-carboxylate
Methyl 5-methoxypyridine-3-carboxylate (CAS 29681-46-7) is a substituted pyridine ester with the molecular formula C8H9NO3 and a molar mass of 167.16 g/mol. Also known as methyl 5-methoxy-3-pyridinecarboxylate, it is a crystalline solid (melting point 54-59 C) used as a heterocyclic building block in organic and medicinal chemistry. Tech Serve Solutions supplies it as a research-grade intermediate for synthesis, with a typical assay of 90%.
- IUPAC
- Methyl 5-methoxy-3-pyridinecarboxylate
- Synonyms
- Methyl 5-methoxypyridine-3-carboxylateMethyl 5-methoxy-3-pyridinecarboxylateMethyl 5-methoxynicotinate5-Methoxynicotinic acid methyl esterCAS 29681-46-7
Heterocyclic building block
Serves as a functionalised pyridine scaffold in organic synthesis, providing both a methoxy group and a methyl ester as handles for further chemical elaboration.
Pharmaceutical and agrochemical intermediate
Used as an intermediate in the preparation of more complex pyridine-based molecules during discovery and process chemistry. Specific end-uses depend on the customer's synthetic route.
Ester and amide chemistry
The methyl ester can be hydrolysed to the corresponding carboxylic acid or converted to amides, supporting the construction of pyridine-3-carboxamide and related derivatives.
Laboratory and research reagent
Applied in research and development settings where a defined methoxy-substituted nicotinate ester is required for route scouting and analogue synthesis.
| Molecular weight | 167.16 |
|---|---|
| Linear formula | CH3OC5H3NCOOCH3 |
| Assay | 90% |
| Melting point | 54-59 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 5-methoxypyridine-3-carboxylate used for?
+
It is used as a heterocyclic building block and synthetic intermediate in organic and medicinal chemistry. The compound provides a methoxy-substituted pyridine ester scaffold that can be elaborated into more complex pyridine derivatives in pharmaceutical, agrochemical and research applications.
What is the CAS number and molecular formula of Methyl 5-methoxypyridine-3-carboxylate?
+
The CAS number is 29681-46-7. Its molecular formula is C8H9NO3 (linear formula CH3OC5H3NCOOCH3), with a molecular weight of 167.16 g/mol and MDL number MFCD09265109.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Methyl 5-methoxypyridine-3-carboxylate as a research-grade intermediate with a typical assay of 90%. We do not represent it as USP, BP or EP pharmacopoeia grade. A certificate of analysis can be provided with each batch.
What are the safety and handling requirements for Methyl 5-methoxypyridine-3-carboxylate?
+
It is classified under GHS with the signal word Danger and pictograms GHS05 and GHS07. The hazard statements are H315 (causes skin irritation), H318 (causes serious eye damage) and H335 (may cause respiratory irritation). Handle with gloves, eye protection and an N95-type dust mask, avoid dust formation, and work in a well-ventilated area. Always consult the Safety Data Sheet before use.
How is Methyl 5-methoxypyridine-3-carboxylate packed, shipped and exported?
+
It is a solid (melting point 54-59 C) supplied in sealed containers sized to your requirement, from gram quantities to larger research lots. As a specialist exporter since 1998, Tech Serve Solutions arranges compliant labelling, documentation and international shipping, with a Safety Data Sheet and certificate of analysis accompanying each consignment.
How do I request a sample or quote?
+
Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged for evaluation where appropriate.
▶ Related products
4-Amino-2-chloropyridine
C5H5ClN2
Heterocyclic Building Blocks
4-Ethynyl-1-methyl-1H-pyrazole
C6H6N2
Heterocyclic Building Blocks
4-Hydroxyquinoline-3-carboxylic acid ethyl ester
C12H11NO3
Heterocyclic Building Blocks
4-isocyanatopyridine
C6H4N2O
Heterocyclic Building Blocks
5-Chloro-2,8-dimethylquinoline
Heterocyclic Building Blocks
5-Chloro-2-methylene-1,3,3-trimethylindoline
Heterocyclic Building Blocks
5-Chloro-2-thiophenecarbonitrile
Heterocyclic Building Blocks
5-ethynyl-1H-pyrazole
C5H4N2
Heterocyclic Building Blocks▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis