Methyl 5-fluoro-2-hydroxybenzoate
Methyl 5-fluoro-2-hydroxybenzoate (CAS: 391-92-4), with the chemical formula FC6H3(OH)CO2CH3 and a molecular weight of 170.14 g/mol, is a fluorinated aromatic compound. It serves as a valuable building block in organic synthesis, particularly in the development of novel molecules for research and development purposes. Its structure, featuring both hydroxyl and ester functionalities alongside a fluorine atom on the benzene ring, offers versatile reactivity for various chemical transformations.

Organic Synthesis Intermediate
Utilised as a key intermediate in the synthesis of more complex organic molecules. Its fluorinated aromatic structure makes it useful in the preparation of compounds where fluorine incorporation is desired for modulating properties.
Pharmaceutical Research
Serves as a building block for the discovery and development of new pharmaceutical agents. The presence of fluorine can influence a molecule's metabolic stability, lipophilicity, and binding affinity.
Materials Science
May be employed in the synthesis of functional materials or polymers where its specific structural features contribute to desired material properties.
Agrochemical Development
Potential application as a precursor in the development of new agrochemical compounds, where fluorinated structures are often investigated for enhanced efficacy.
| Molecular weight | 170.14 |
|---|---|
| Linear formula | FC6H3(OH)CO2CH3 |
| Assay | 97% |
| Boiling point | 50 °C/0.15 mmHg(lit.) |
| Melting point | 30-34 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 5-fluoro-2-hydroxybenzoate used for?
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Methyl 5-fluoro-2-hydroxybenzoate is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and the development of novel organic compounds where fluorine incorporation is beneficial.
What are the CAS number and chemical formula for Methyl 5-fluoro-2-hydroxybenzoate?
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The CAS number is 391-92-4, and the chemical formula is FC6H3(OH)CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 5-fluoro-2-hydroxybenzoate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Methyl 5-fluoro-2-hydroxybenzoate be handled safely?
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As indicated by its GHS07 symbol and Warning signal word, Methyl 5-fluoro-2-hydroxybenzoate may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95 US recommended), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is Methyl 5-fluoro-2-hydroxybenzoate packed and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, offering this product for international shipment.
How can I request a quote or sample of Methyl 5-fluoro-2-hydroxybenzoate?
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Please contact our sales team via the website to request a quote or a sample of Methyl 5-fluoro-2-hydroxybenzoate.
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