Methyl 5-chloro-2-pyrazinecarboxylate
Methyl 5-chloro-2-pyrazinecarboxylate (CAS: 33332-25-1), with the molecular formula C6H5ClN2O2 and a molecular weight of 172.57 g/mol, is a halogenated heterocyclic building block. It is primarily utilised in chemical synthesis, serving as a key intermediate in the preparation of more complex molecules. Its structure features a pyrazine ring substituted with a chlorine atom and a methyl ester group, offering versatile reactivity for further chemical transformations.

Organic Synthesis Intermediate
Serves as a crucial building block in the synthesis of novel organic compounds. Its functional groups allow for diverse chemical reactions, enabling the construction of complex molecular architectures.
Pharmaceutical Research
Used in the development of new active pharmaceutical ingredients (APIs). The pyrazine core is present in various biologically active molecules, making this compound a valuable starting material.
Agrochemical Development
Can be employed in the research and synthesis of new agrochemicals. Its heterocyclic structure may contribute to the development of novel pesticides or herbicides.
| Molecular weight | 172.57 |
|---|---|
| Empirical formula | C6H5ClN2O2 |
| Assay | ≥98.0% (HPLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 5-chloro-2-pyrazinecarboxylate used for?
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Methyl 5-chloro-2-pyrazinecarboxylate is primarily used as a building block in organic synthesis, particularly in the development of pharmaceutical and agrochemical compounds.
What is the CAS number and molecular formula for Methyl 5-chloro-2-pyrazinecarboxylate?
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The CAS number is 33332-25-1, and the molecular formula is C6H5ClN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 5-chloro-2-pyrazinecarboxylate with a minimum assay of ≥98.0% (HPLC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or food grade.
How should Methyl 5-chloro-2-pyrazinecarboxylate be handled?
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This compound is classified as a Warning. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation.
Is Methyl 5-chloro-2-pyrazinecarboxylate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Methyl 5-chloro-2-pyrazinecarboxylate, adhering to international shipping regulations.
How can I request a quote or sample?
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To request a quote or sample of Methyl 5-chloro-2-pyrazinecarboxylate, please use the contact form on our website or contact our sales department directly with your requirements.
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