Methyl 4-fluorobenzoate
Methyl 4-fluorobenzoate (CAS: 403-33-8) is an organic ester with the chemical formula FC6H4CO2CH3 and a molecular weight of 154.14 g/mol. This compound serves as a valuable fluorinated building block in organic synthesis. It is primarily utilised in the creation of complex molecules, including trisubstituted imidazole derivatives for research and development purposes within the chemical industry.
Synthesis of Imidazole Derivatives
Methyl 4-fluorobenzoate is employed as a key intermediate in the synthesis of specific trisubstituted imidazole derivatives. These molecules may incorporate a 4-fluorophenyl group, a pyrimidine ring, and a benzyl moiety substituted with CN or CONH2 groups.
Fluorinated Organic Building Block
As a fluorinated organic building block, this ester provides a reactive site for introducing a 4-fluorobenzoyl group into larger molecular structures. Its utility spans various research areas in organic chemistry.
Chemical Research and Development
This compound is supplied for laboratory use and chemical research, enabling chemists to explore novel synthetic pathways and develop new chemical entities.
| Molecular weight | 154.14 |
|---|---|
| Linear formula | FC6H4CO2CH3 |
| Assay | 98% |
| Boiling point | 90-92 °C/20 mmHg(lit.) |
| Density | 1.192 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.494(lit.) |
| Application | Methyl 4-fluorobenzoate can be used in the synthesis of trisubstituted imidazole derivatives containing a 4-fluorophenyl group, a pyrimidine ring, and a CN- or CONH2-substituted benzyl moiety1. |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 78 °C / 172.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4-fluorobenzoate used for?
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Methyl 4-fluorobenzoate is primarily used as a building block in organic synthesis, particularly for the preparation of trisubstituted imidazole derivatives and other fluorinated organic compounds for research.
What are the CAS number and chemical formula for Methyl 4-fluorobenzoate?
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The CAS number for Methyl 4-fluorobenzoate is 403-33-8, and its chemical formula is FC6H4CO2CH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4-fluorobenzoate with an assay of 98%. We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should Methyl 4-fluorobenzoate be handled safely?
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Methyl 4-fluorobenzoate is classified as dangerous. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye damage (H318), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area.
Is Methyl 4-fluorobenzoate a controlled substance?
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The provided data does not indicate that Methyl 4-fluorobenzoate is a controlled substance.
How is Methyl 4-fluorobenzoate packed and shipped?
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Methyl 4-fluorobenzoate is classified under UN 1993, Packing Group III for transport. Specific packing details are available upon request, and TSS is experienced in global export.
How can I request a quote or sample?
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Please contact our sales team with your requirements to request a quote or a sample of Methyl 4-fluorobenzoate.
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