Methyl 4-chloro-4-oxobutyrate
Methyl 4-chloro-4-oxobutyrate (CAS 1490-25-1) is an organic compound with the linear formula CH₃OCOCH₂CH₂COCl and a molecular weight of 150.56 g/mol. This acid halide serves as a valuable intermediate in organic synthesis. Its reactive acyl chloride group allows for facile derivatisation, making it a useful building block for constructing more complex molecules in research and development settings.
- IUPAC
- 3-(Carbomethoxy)propionyl chloride,Methyl 3-(chloroformyl)propionate,Methyl succinyl chloride,Succinic acid monomethylester chloride
- Synonyms
- 3-(Carbomethoxy)propionyl chlorideMethyl 3-(chloroformyl)propionateMethyl succinyl chlorideSuccinic acid monomethylester chloride
Organic Synthesis Intermediate
Methyl 4-chloro-4-oxobutyrate is employed as a key building block in the synthesis of various organic compounds. Its acyl chloride functionality readily reacts with nucleophiles, facilitating the formation of esters, amides, and other derivatives.
Pharmaceutical Research
This compound can be utilised in the development of novel pharmaceutical agents. Its structure allows for incorporation into diverse molecular frameworks during drug discovery and medicinal chemistry research.
Fine Chemical Production
As a reactive intermediate, it finds application in the production of specialised fine chemicals. It enables the introduction of specific functional groups and structural motifs into target molecules.
| Molecular weight | 150.56 |
|---|---|
| Linear formula | CH3OCOCH2CH2COCl |
| Assay | 97% |
| Boiling point | 58-65 °C/3 mmHg(lit.) |
| Density | 1.223 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.44(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-37 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4-chloro-4-oxobutyrate used for?
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Methyl 4-chloro-4-oxobutyrate is primarily used as an intermediate in organic synthesis and in pharmaceutical research for developing new chemical entities.
What is the CAS number and formula for Methyl 4-chloro-4-oxobutyrate?
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The CAS number is 1490-25-1 and the linear formula is CH₃OCOCH₂CH₂COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4-chloro-4-oxobutyrate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Methyl 4-chloro-4-oxobutyrate be handled safely?
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This compound is dangerous and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including face shields, respirators, gloves, and goggles. Ensure adequate ventilation.
Is Methyl 4-chloro-4-oxobutyrate available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including Methyl 4-chloro-4-oxobutyrate.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales team through the website or by phone.
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