Methyl 4,6-dimethoxy-2-indolecarboxylate
Methyl 4,6-dimethoxy-2-indolecarboxylate (CAS 105776-13-4) is a chemical compound with the molecular formula C12H13NO4 and a molecular weight of 235.24 g/mol. It functions as a valuable building block in organic synthesis, particularly within heterocyclic chemistry. Its utility is demonstrated in various chemical reactions, including its role as a reactant in nitration processes and in the preparation of specific pharmaceutical intermediates.
- Synonyms
- C12H13NO4Methyl 4,6-dimethoxy-2-indolecarboxylate
Reactant in Nitration Reactions
This indole derivative serves as a reactant in nitration reactions, commonly employing nitric acid as the nitrating agent. This process is a fundamental step in modifying the indole core for further synthetic elaboration.
Preparation of TNF-α Inhibitors
Methyl 4,6-dimethoxy-2-indolecarboxylate is utilised in the synthesis of light-dependent tumor necrosis factor-α (TNF-α) inhibitors. This application highlights its importance in the development of novel therapeutic agents.
Heterocyclic Building Block
As a functionalised indole, it acts as a versatile building block in heterocyclic synthesis. Its structure allows for diverse chemical transformations, making it useful for constructing complex organic molecules.
| Molecular weight | 235.24 |
|---|---|
| Empirical formula | C12H13NO4 |
| Assay | 99% |
| Application | • reactant in nitration reactions with nitric acid1• reactant in preparation of light-dependent tumor necrosis factor-α inhibitors2 |
| Melting point | 182-183 °C(lit.) |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl 4,6-dimethoxy-2-indolecarboxylate used for?
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Methyl 4,6-dimethoxy-2-indolecarboxylate is used as a reactant in nitration reactions and in the preparation of light-dependent tumor necrosis factor-α inhibitors. It also serves as a versatile building block in chemical synthesis.
What are the CAS number and molecular formula for Methyl 4,6-dimethoxy-2-indolecarboxylate?
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The CAS number is 105776-13-4, and the molecular formula is C12H13NO4 (or C12H13NO4 by empirical formula Hill notation).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl 4,6-dimethoxy-2-indolecarboxylate with a purity of 99% (assay). This product is suitable for research and chemical synthesis purposes. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for this compound?
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According to the provided data, this compound has a WGK Germany classification of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area.
Is Methyl 4,6-dimethoxy-2-indolecarboxylate a controlled substance?
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The provided data does not indicate that Methyl 4,6-dimethoxy-2-indolecarboxylate is a controlled substance.
How can I request a quote or sample?
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To request a quote or a sample of Methyl 4,6-dimethoxy-2-indolecarboxylate, please contact the Tech Serve Solutions sales team through the website or via direct enquiry.
How is Methyl 4,6-dimethoxy-2-indolecarboxylate packed and exported?
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Tech Serve Solutions packs and exports fine chemicals with rigorous attention to safety and regulatory compliance, ensuring secure transit for global distribution.
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