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(Methoxymethyl)diphenylphosphine oxide

CAS 4455-77-0(C6H5)2P(O)CH2OCH3Catalysis & Inorganic

(Methoxymethyl)diphenylphosphine oxide (CAS: 4455-77-0) is a chemical compound with the linear formula (C6H5)2P(O)CH2OCH3 and a molecular weight of 246.24 g/mol. This phosphine oxide derivative is primarily utilised as a catalyst in various organic synthesis reactions, including Pauson-Khand and hydroformylation processes. Its specific chemical structure lends itself to applications requiring precise catalytic activity in fine chemical and pharmaceutical intermediate production.

IUPAC
Diphenyl(methoxymethyl)phosphine oxide
Synonyms
Diphenyl(methoxymethyl)phosphine oxide
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(Methoxymethyl)diphenylphosphine oxide ((C6H5)2P(O)CH2OCH3) — chemical structure, CAS 4455-77-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Chemical SynthesisPhosphine CompoundsPhosphine Ligands
01 /Applications

Pauson-Khand Reaction Catalyst

Serves as a catalyst for molybdenum hexacarbonyl-mediated Pauson-Khand reactions, facilitating the synthesis of cyclic ketones.

Hydroformylation Catalyst

Acts as a catalyst in rhodium-catalyzed hydroformylation reactions, a key process for converting alkenes into aldehydes.

Organic Synthesis Reagent

Employed in general organic synthesis, particularly where phosphine oxide functionalities are required for directed reactions or as intermediates.

02 /Properties
Molecular weight246.24
Linear formula(C6H5)2P(O)CH2OCH3
Assay98%
ApplicationCatalyst for:• Molybdenum hexacarbonyl-mediated Pauson-Khand reactions1• Rhodium-catalyzed hydroformylation reaction2
Melting point115-117 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
4455-77-0
MDL number
MFCD00015451
PubChem substance
24868881
Beilstein registry
649558
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (Methoxymethyl)diphenylphosphine oxide used for?

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(Methoxymethyl)diphenylphosphine oxide is used as a catalyst in reactions such as molybdenum hexacarbonyl-mediated Pauson-Khand reactions and rhodium-catalyzed hydroformylation.

What is the CAS number and chemical formula for (Methoxymethyl)diphenylphosphine oxide?

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The CAS number is 4455-77-0 and the linear chemical formula is (C6H5)2P(O)CH2OCH3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies (Methoxymethyl)diphenylphosphine oxide with a minimum purity of 98%. TSS does not represent this product as USP, BP, or EP grade.

How should (Methoxymethyl)diphenylphosphine oxide be handled safely?

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Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as harmful if swallowed (H302).

How is (Methoxymethyl)diphenylphosphine oxide packed and exported?

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This product is carefully packed to ensure stability during transit and is available for global export by Tech Serve Solutions.

How can I request a sample or a quote for (Methoxymethyl)diphenylphosphine oxide?

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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone.

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