Methoctramine hydrate
Methoctramine hydrate (CAS: 104807-46-7) is a chemical compound with the formula C36H62N4O2 · 4HCl · xH2O. Characterised as a white solid, it has a molecular weight of 728.75 g/mol (anhydrous basis). Methoctramine hydrate functions primarily as a muscarinic acetylcholine receptor antagonist. It is a valuable tool in scientific research, particularly within cell biology and neuroscience, for investigating cholinergic neurotransmission and related cellular signalling pathways.
- IUPAC
- Methoctramine tetrahydrochloride hydrate,N,N′-bis[6-[[(2-Methoxyphenyl)methyl]amino]hexyl]-1,8-octane diamine tetrahydrochloride hydrate
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Pharmacological Research Tool
Methoctramine hydrate serves as a selective antagonist for muscarinic acetylcholine receptors (mAChRs). Its application is crucial for in vitro and in vivo studies aimed at understanding the physiological roles of different mAChR subtypes, particularly M2 and M4 receptors, in various biological systems.
Neuroscience Research
In neuroscience, this compound aids in exploring the intricacies of cholinergic neurotransmission. Researchers utilise it to investigate the involvement of muscarinic receptors in neuronal function, synaptic plasticity, and the development of neurological disorders.
Cell Signaling Investigations
Methoctramine hydrate is employed to dissect cellular signalling cascades regulated by mAChRs. By blocking these receptors, scientists can elucidate downstream effects and identify key signalling molecules involved in cellular responses.
| Molecular weight | 728.75 (anhydrous basis) |
|---|---|
| Empirical formula | C36H62N4O2 · 4HCl · xH2O |
| Assay | ≥97% (NMR) |
| Form | solid |
| Colour | white |
| Solubility | H2O: >20 mg/mL |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... CHRM2(1129) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methoctramine hydrate used for?
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Methoctramine hydrate is primarily used as a research chemical, functioning as an antagonist for muscarinic acetylcholine receptors, particularly in studies related to neuroscience, cell signaling, and pharmacology.
What is the CAS number and formula for Methoctramine hydrate?
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The CAS number for the anhydrous form is 104807-46-7, and the formula is C36H62N4O2 · 4HCl · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methoctramine hydrate with a purity of ≥97% (NMR). This is a research grade chemical and is not represented as USP, BP, or EP grade.
How should Methoctramine hydrate be handled and stored?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a P1 (EN143) or N95 respirator. Methoctramine hydrate should be stored at 2-8°C.
Is Methoctramine hydrate a controlled substance?
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The provided data does not indicate that Methoctramine hydrate is a controlled substance.
How is Methoctramine hydrate packed and shipped?
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This product is typically supplied as a white solid. Details regarding specific packing and international shipping protocols can be provided upon request.
How can I request a quote or sample for Methoctramine hydrate?
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To request a quote or a sample, please contact the Tech Serve Solutions sales team through our website or by direct inquiry, providing your specific requirements.
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