(±)-Methadone hydrochloride

CAS 1095-90-5C21H27NO · HClBiochemicals & Reagents

(±)-Methadone hydrochloride (CAS: 1095-90-5, Formula: C21H27NO · HCl, MW: 345.91) is a synthetic opioid. It is primarily recognised for its role in opioid maintenance therapy for individuals with opioid dependence and as a potent analgesic for severe chronic pain management. This compound is supplied by Tech Serve Solutions as a white to off-white powder with a minimum purity of 98% (TLC).

IUPAC: 6-Dimethylamino-4,4-diphenylheptan-3-one hydrochloride

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(±)-Methadone hydrochloride (C21H27NO · HCl) — chemical structure, CAS 1095-90-5; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsCalcium Channel ModulatorsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesInhibitors and ActivatorsIon Channels

01 /Applications

Opioid Maintenance Therapy

Methadone hydrochloride is a crucial pharmaceutical agent used in medically supervised programs to manage opioid addiction. It helps reduce withdrawal symptoms and cravings, enabling individuals to stabilise their lives.

Analgesia for Chronic Pain

Due to its potent activity, methadone hydrochloride is prescribed for the relief of severe chronic pain, particularly when other analgesics are insufficient. Its long duration of action is beneficial for continuous pain management.

Research and Development

As a well-characterised opioid agonist, methadone hydrochloride serves as a valuable tool in pharmacological research. It is used in studies investigating opioid receptor mechanisms, pain pathways, and addiction research.

02 /Properties

Molecular weight	345.91
Empirical formula	C21H27NO · HCl
Assay	≥98% (TLC)
Form	powder
Colour	white to off-white
Solubility	H2O: >50 mg/mL, clear, colorless to yellow

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash thoroughly after handling
P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1095-90-5

MDL number

MFCD00058014

PubChem substance

24896546

05 /Additional specifications

Drug Control	USDEA Schedule II; Home Office Schedule 2; stup

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (±)-Methadone hydrochloride used for?

(±)-Methadone hydrochloride is used for opioid maintenance therapy and as an analgesic for severe chronic pain. It is also utilised in research settings.

What is the CAS number and formula for Methadone hydrochloride?

The CAS number is 1095-90-5 and the empirical formula is C21H27NO · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (±)-Methadone hydrochloride with a minimum purity of 98% (TLC). TSS does not represent this product as USP, BP, EP, or any other pharmacopoeial grade.

How is Methadone hydrochloride handled and shipped?

Methadone hydrochloride is classified under UN 2811 6.1 / PGII, requiring careful handling due to its toxicity (H300). Personal protective equipment such as eyeshields, faceshields, gloves, and P2 respirator cartridges should be used. It is shipped as a hazardous material.