Maprotiline hydrochloride
Maprotiline hydrochloride (CAS: 10347-81-6) is a tetracyclic antidepressant with the molecular formula C20H23N · HCl and a molecular weight of 313.86 g/mol. Supplied as a white powder, this compound is primarily used in biochemical research as a tool for studying neurotransmission, particularly its effects on the noradrenergic system. Its well-defined chemical properties make it valuable for in vitro and in vivo investigations within neuroscience and cell signalling.
- IUPAC
- 9-(γ-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracene hydrochloride

Neuroscience Research
Maprotiline hydrochloride serves as a research chemical for investigating noradrenergic neurotransmission and its role in neurological pathways. It is utilized in studies exploring mood regulation, stress responses, and the mechanisms underlying neurological disorders.
Biochemical Studies
This compound is employed in biochemical assays to understand the interactions with biogenic amine transporters. Its specific action allows researchers to explore cellular signalling cascades and receptor modulation within neuroscience research.
Drug Discovery and Development
As an approved therapeutic agent and bioactive small molecule, maprotiline hydrochloride can be used as a reference standard or tool compound in the early stages of drug discovery. Researchers may use it to validate targets related to depression and other central nervous system disorders.
| Molecular weight | 313.86 |
|---|---|
| Empirical formula | C20H23N · HCl |
| Assay | >99% (HPLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble50 mg/mL |

Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Maprotiline hydrochloride used for?
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Maprotiline hydrochloride is used as a research chemical primarily in neuroscience and biochemical studies, particularly for investigating noradrenergic neurotransmission and biogenic amine transport. It is also relevant in drug discovery and development related to central nervous system disorders.
What are the CAS number and formula for Maprotiline hydrochloride?
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The CAS number for Maprotiline hydrochloride is 10347-81-6, and its empirical formula is C20H23N · HCl.
What grade and purity does Tech Serve Solutions supply for Maprotiline hydrochloride?
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Tech Serve Solutions supplies Maprotiline hydrochloride with a purity of >99% (HPLC). This product is intended for research and laboratory use. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades unless explicitly stated in the product specifications.
How should Maprotiline hydrochloride be handled safely?
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Maprotiline hydrochloride is classified as harmful if swallowed (H302) and requires careful handling. Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation.
Is Maprotiline hydrochloride a controlled substance?
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The provided data does not indicate that Maprotiline hydrochloride is a controlled substance. However, users should always verify local regulations.
How is Maprotiline hydrochloride packed, shipped, and exported?
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Maprotiline hydrochloride is supplied as a white powder. As a global supplier, Tech Serve Solutions exports chemicals worldwide, adhering to all relevant shipping and customs regulations for international distribution.
How can I request a sample or quote for Maprotiline hydrochloride?
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To request a sample or a quote for Maprotiline hydrochloride, please contact our sales team through the website or by calling our direct line. We are happy to assist with your research needs.
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