Lithocholic acid
Lithocholic acid (CAS 434-13-9), with the molecular formula C24H40O3 and a molecular weight of 376.57 g/mol, is a secondary bile acid. It is a sterol lipid derivative and a biochemical reagent. Lithocholic acid is primarily recognised for its role in biological systems and serves as a valuable compound in research and development settings.
- IUPAC
- 3α-Hydroxy-5β-cholan-24-oic acid,3α-Hydroxy-5β-cholanic acid,5β-Cholan-24-oic acid-3α-ol
- Synonyms
- 3alpha-Hydroxy-5beta-cholan-24-oic acid3alpha-Hydroxy-5beta-cholanic acid5beta-Cholan-24-oic acid-3alpha-ol
Biochemical Research
Lithocholic acid is employed in biochemical studies to investigate bile acid metabolism, nuclear receptor signalling pathways (such as FXR and LXR), and cellular processes. Its specific biological activities make it a key tool for understanding lipid homeostasis and related diseases.
Organic Synthesis Intermediate
This compound can serve as a starting material or intermediate in the synthesis of more complex steroid derivatives and related molecules. Its distinct structure facilitates modifications for creating novel chemical entities for research purposes.
Cell Biology Investigations
It is used in cell culture and biological assays to study the effects of bile acids on cell function, viability, and differentiation. Researchers utilise lithocholic acid to explore its cytotoxic and cytoprotective properties.
| Molecular weight | 376.57 |
|---|---|
| Empirical formula | C24H40O3 |
| Assay | ≥95% |
| Optical activity | [α]20/D +35±1°, c = 1% in ethanol |
| Impurities tested | ~1% deoxycholic acid (TLC) |
| Melting point | 183-188 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lithocholic acid used for?
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Lithocholic acid is used in biochemical research to study bile acid metabolism and signalling pathways, as an intermediate in organic synthesis, and in cell biology investigations to understand its effects on cell function.
What is the CAS number and formula for Lithocholic acid?
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The CAS number for Lithocholic acid is 434-13-9, and its empirical formula is C24H40O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Lithocholic acid with an assay of ≥95%. We do not represent this product as USP, BP, or EP grade.
How should Lithocholic acid be handled?
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Handle Lithocholic acid with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK Germany 2.
How is Lithocholic acid shipped?
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Tech Serve Solutions exports and supplies Lithocholic acid globally, adhering to all necessary shipping regulations for chemical compounds.
How can I request a sample or quote for Lithocholic acid?
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To request a sample or a quote for Lithocholic acid, please contact our sales team through the website or by phone.
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