m-Tolylmagnesium chloride solution
m-Tolylmagnesium chloride solution (CAS 121905-60-0), with the linear formula CH3C6H4MgCl and a molecular weight of 150.89 g/mol, is a valuable organometallic reagent. Supplied as a 1.0 M solution in THF, it is frequently employed in organic synthesis. This Grignard reagent facilitates carbon-carbon bond formation, proving indispensable in the preparation of complex organic molecules and pharmaceutical intermediates.
Grignard Reagent in Organic Synthesis
m-Tolylmagnesium chloride solution serves as a potent nucleophile for introducing the m-tolyl group into organic molecules. It is widely used in the formation of new carbon-carbon bonds, essential for constructing complex molecular architectures.
Pharmaceutical Intermediate Synthesis
This compound is a key building block in the multi-step synthesis of various pharmaceutical intermediates. Its reactivity allows for the precise introduction of the m-tolyl moiety, a common structural feature in drug candidates.
Chemical Research and Development
As a versatile organometallic reagent, m-Tolylmagnesium chloride solution finds application in academic and industrial research for exploring novel synthetic pathways and developing new chemical entities.
| Molecular weight | 150.89 |
|---|---|
| Linear formula | CH3C6H4MgCl |
| Density | 0.956 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | -21 °C / -5.8 °F |
| Transport (UN / ADR) | UN 3399 4.3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is m-Tolylmagnesium chloride solution used for?
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m-Tolylmagnesium chloride solution is primarily used as a Grignard reagent in organic synthesis for carbon-carbon bond formation, particularly in the preparation of pharmaceutical intermediates and complex organic molecules.
What is the CAS number and formula for m-Tolylmagnesium chloride solution?
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The CAS number is 121905-60-0 and the linear formula is CH3C6H4MgCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies m-Tolylmagnesium chloride solution at a concentration of 1.0 M in THF. We do not represent this product as USP, BP, or EP grade. Please refer to the product specifications for detailed purity information.
How should m-Tolylmagnesium chloride solution be handled and stored?
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This solution is highly flammable and corrosive, reacting violently with water and potentially forming explosive peroxides. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment including gloves, goggles, and face shields. Store in a cool, dry, well-ventilated place away from heat and ignition sources, and incompatible materials. Refer to the safety data sheet for comprehensive handling and storage instructions.
How is m-Tolylmagnesium chloride solution shipped and exported?
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m-Tolylmagnesium chloride solution is classified under UN 3399, hazard class 4.3, packing group II, indicating it is a dangerous good requiring specialised shipping and handling. Tech Serve Solutions is experienced in exporting such materials globally, adhering to all relevant international regulations.
How can I request a sample or quote for m-Tolylmagnesium chloride solution?
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To request a sample or a quote, please contact our sales department through the contact information provided on our website, specifying the product name, CAS number, and required quantity.
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