Indole-2-boronic acid pinacol ester
Indole-2-boronic acid pinacol ester (CAS: 476004-81-6), with the empirical formula C14H18BNO2 and a molecular weight of 243.11 g/mol, is a valuable organoboron compound. It serves as a key building block in organic synthesis, particularly in cross-coupling reactions. This ester derivative of indole-2-boronic acid offers enhanced stability and ease of handling, making it a preferred reagent for researchers and industrial chemists involved in complex molecule construction.
- IUPAC
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole,2-Indoleboronic acid pinacol ester
- Synonyms
- 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole2-Indoleboronic acid pinacol ester
Suzuki-Miyaura Cross-Coupling Reactions
This boronate ester is an excellent substrate for Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. Its indole core can be efficiently incorporated into larger molecular frameworks.
Heterocyclic Compound Synthesis
It is widely employed in the synthesis of diverse indole-containing heterocyclic compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials science. The boronate ester functionality allows for regioselective functionalization.
Medicinal Chemistry and Drug Discovery
The indole scaffold is a privileged structure in medicinal chemistry. Indole-2-boronic acid pinacol ester facilitates the development of novel drug candidates by enabling the modular assembly of complex indole derivatives with potential therapeutic activities.
Materials Science
The unique electronic and structural properties of indole derivatives make them useful in advanced materials. This reagent can be used to synthesize novel organic electronic materials or functional polymers incorporating the indole moiety.
| Molecular weight | 243.11 |
|---|---|
| Empirical formula | C14H18BNO2 |
| Assay | 95% |
| Melting point | 101-102 °C |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Indole-2-boronic acid pinacol ester used for?
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Indole-2-boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions and the construction of complex heterocyclic compounds, including those relevant to medicinal chemistry and materials science.
What is the CAS number and formula for Indole-2-boronic acid pinacol ester?
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The CAS number is 476004-81-6 and the empirical formula is C14H18BNO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Indole-2-boronic acid pinacol ester with a minimum purity of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling considerations for this compound?
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Indole-2-boronic acid pinacol ester is classified under WGK 2 in Germany, indicating it is hazardous to water. Appropriate personal protective equipment should be worn during handling, and it should be stored in a cool, dry place away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed information.
How is Indole-2-boronic acid pinacol ester packed, shipped, and exported?
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Tech Serve Solutions securely packs and ships this chemical in compliance with all relevant national and international regulations for hazardous materials. We have extensive experience in exporting fine chemicals globally.
How can I request a sample or a quote?
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To request a sample or a quote for Indole-2-boronic acid pinacol ester, please contact our sales team through the website or by phone, providing your contact details and the quantity required.
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