Leupeptin trifluoroacetate salt
Leupeptin trifluoroacetate salt (CAS: 147385-61-3) is a microbial-derived peptide inhibitor with a molecular weight of 426.55 (free base basis). This compound is recognised for its ability to inhibit serine proteases, including trypsin and plasmin, as well as cysteine proteases like papain and cathepsins. It is widely employed in biochemical research for protein purification and enzyme activity studies.
- IUPAC
- Acetyl-Leu-Leu-Arg-al trifluoroacetate salt
Protease Inhibition
Leupeptin trifluoroacetate salt effectively inhibits a broad spectrum of serine and cysteine proteases, making it invaluable for preventing protein degradation during extraction and purification procedures in various research settings.
Biochemical Research
It serves as a critical reagent in molecular biology and biochemistry laboratories to study enzyme mechanisms, particularly those involving proteases like calpains and cathepsins, and to investigate cellular processes such as apoptosis.
Cell Biology Studies
This compound is utilised in cell culture to modulate protease activity and study its impact on cellular signalling pathways, protein turnover, and disease progression.
| Molecular weight | 426.55 (free base basis) |
|---|---|
| Empirical formula | C20H38N6O4 · xC2HF3O2 |
| Assay | ≥90% (HPLC) |
| Solubility | H2O: soluble10 mM (Solutions are stable only a few hours. Stock solutions are stable up to 6 months at −20 °C.) |
| Storage temperature | −20°C |
| Biological source | microbial |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Leupeptin trifluoroacetate salt used for?
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Leupeptin trifluoroacetate salt is primarily used as a broad-spectrum protease inhibitor in biochemical research to prevent protein degradation during isolation and purification, and for studying protease activity in biological systems.
What is the CAS number and formula for Leupeptin trifluoroacetate salt?
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The CAS number for Leupeptin trifluoroacetate salt is 147385-61-3. Its empirical formula is C20H38N6O4 · xC2HF3O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Leupeptin trifluoroacetate salt with an assay of ≥90% (HPLC). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should Leupeptin trifluoroacetate salt be handled safely?
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When handling Leupeptin trifluoroacetate salt, appropriate personal protective equipment should be used, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Refer to the safety data sheet for comprehensive handling instructions.
How is Leupeptin trifluoroacetate salt shipped and exported by TSS?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, ensuring reliable shipping and export services for Leupeptin trifluoroacetate salt worldwide.
How can I request a sample or quote for Leupeptin trifluoroacetate salt?
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To request a sample or a quote for Leupeptin trifluoroacetate salt, please contact the Tech Serve Solutions sales team through our website or by phone.
Is Leupeptin trifluoroacetate salt a controlled substance?
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The provided data does not indicate that Leupeptin trifluoroacetate salt is a controlled substance.
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