L-Homocysteine
L-Homocysteine (CAS 6027-13-0) is a non-proteinogenic amino acid with the linear formula HSCH2CH2CH(NH2)COOH and a molecular weight of 135.18 g/mol. It is a key intermediate in methionine metabolism. L-Homocysteine is supplied by TSS with an assay of ≥98.0% and is primarily used in biochemical research and as a reagent in laboratory settings.
- IUPAC
- (S)-2-Amino-4-mercaptobutyric acid
- Synonyms
- (S)-2-Amino-4-mercaptobutyric acid

Biochemical Research
L-Homocysteine is utilised in research to study amino acid metabolism and its role in biological pathways. Its involvement in methylation and transsulfuration pathways makes it a valuable tool for investigating cellular processes.
Chemical Reagent
As a specialised reagent, L-Homocysteine is employed in various laboratory analyses and synthetic procedures. Its unique thiol group allows for diverse chemical reactions.
Metabolism Studies
Researchers use L-Homocysteine to understand the complex biochemical pathways involving sulfur-containing amino acids. This includes studies on related genetic disorders and metabolic dysfunctions.
| Molecular weight | 135.18 |
|---|---|
| Linear formula | HSCH2CH2CH(NH2)COOH |
| Assay | ≥98.0% (NT) |
| Optical activity | [α]/D 25.5±1.5°, c = 1 in 1 M HCl |
| Storage temperature | −20°C |

Hazard statements
- H302Harmful if swallowed
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Homocysteine used for?
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L-Homocysteine is primarily used in biochemical research and as a laboratory reagent for studying amino acid metabolism and related biological pathways.
What is the CAS number and chemical formula for L-Homocysteine?
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The CAS number for L-Homocysteine is 6027-13-0 and its linear formula is HSCH2CH2CH(NH2)COOH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-Homocysteine with an assay of ≥98.0%. We do not represent this product as USP, BP, or EP grade.
How should L-Homocysteine be handled and stored?
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L-Homocysteine is classified as harmful if swallowed (H302) and should be handled with appropriate personal protective equipment. It is recommended to store the product at −20°C.
Can L-Homocysteine be safely shipped and exported?
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Yes, L-Homocysteine can be safely shipped and exported by Tech Serve Solutions, adhering to all necessary regulations for chemical transport.
How can I request a sample or quote for L-Homocysteine?
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To request a sample or quote for L-Homocysteine, please contact our sales team through the website or by phone.
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