L-Histidine dihydrochloride
L-Histidine dihydrochloride (CAS: 6027-02-7, C6H9N3O2 · 2HCl) is a stable, white crystalline salt derived from the essential amino acid L-histidine. With a molecular weight of 228.08 g/mol, it is highly soluble in water. This compound serves as a crucial building block and reagent in various biochemical research and laboratory applications, often utilised in cell culture media and as a component in specialised chemical syntheses.

Biochemical Research Reagent
Utilised as a reagent in biochemical studies, particularly those involving amino acid derivatives and their physiological roles. Its dihydrochloride form offers enhanced solubility and stability for experimental use.
Cell Culture Media Component
Incorporated into specific cell culture media formulations to provide essential nutrients or buffering capacity. It supports cell growth and viability in vitro.
Chemical Synthesis Intermediate
Acts as an intermediate or building block in the synthesis of more complex organic molecules and pharmaceutical compounds. Its specific functional groups allow for targeted chemical modifications.
| Molecular weight | 228.08 |
|---|---|
| Empirical formula | C6H9N3O2 · 2HCl |
| Assay | ≥99.0% (AT) |
| Solubility | H2O: solublesaline: soluble |
| Optical activity | [α]20/D +6.5±1°, c = 8% in H2O |
| Melting point | 240-245 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | As: ≤0.1 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgNH4+: ≤500 mg/kgNi: ≤5 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | sulfate (SO42-): ≤50 mg/kg |
| Ignition residue | ≤0.1% (as SO4) |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Histidine dihydrochloride used for?
+
L-Histidine dihydrochloride is primarily used as a reagent in biochemical research, as a component in cell culture media, and as an intermediate in chemical synthesis.
What is the CAS number and formula for L-Histidine dihydrochloride?
+
The CAS number is 6027-02-7 and the empirical formula (Hill notation) is C6H9N3O2 · 2HCl.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies L-Histidine dihydrochloride with an assay of ≥99.0% (AT). We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated.
How should L-Histidine dihydrochloride be handled?
+
Handle L-Histidine dihydrochloride with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a German Water Hazard Class (WGK) of 3, indicating it is hazardous to water.
Is L-Histidine dihydrochloride a controlled substance?
+
The provided data does not indicate that L-Histidine dihydrochloride (CAS: 6027-02-7) is a controlled substance.
How is L-Histidine dihydrochloride packed and shipped?
+
Tech Serve Solutions offers L-Histidine dihydrochloride for global export, packed securely to maintain product integrity during transit. Specific packaging details are available upon request.
How can I request a sample or quote for L-Histidine dihydrochloride?
+
To request a sample or a quote for L-Histidine dihydrochloride, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents

(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis