L-Glutamic acid-15N
L-Glutamic acid-15N (CAS: 21160-87-2), with the molecular formula HO2C(CH2)2CH(15NH)CO2H and a molecular weight of 148.12 g/mol, is an isotopically labelled derivative of the common amino acid L-glutamic acid. Utilising the stable isotope 15N, this compound serves as a critical tool in metabolic studies, proteomics, and biomolecular NMR spectroscopy for tracing metabolic pathways and elucidating protein structures.

Biomolecular NMR Spectroscopy
L-Glutamic acid-15N is employed in NMR studies to investigate protein structure and dynamics. The incorporation of the 15N isotope allows for specific signal assignment and enhanced resolution in protein spectra.
Proteomics and Metabolic Pathway Tracing
This labelled amino acid is a valuable tracer in metabolic research, enabling scientists to follow the fate of nitrogen atoms within cellular pathways and complex biological systems.
Mass Spectrometry Applications
The defined isotopic enrichment of 15N in L-Glutamic acid-15N makes it suitable as an internal standard or tracer in quantitative mass spectrometry experiments, particularly in proteomics.
| Molecular weight | 148.12 |
|---|---|
| Linear formula | HO2C(CH2)2CH(15NH)CO2H |
| Optical activity | [α]25/D +31.0°, c = 2 in 5 M HCl |
| Melting point | 205 °C (dec.)(lit.) |
| Isotopic Purity | 98 atom % 15N |
|---|---|
| Mol Wt | mol wt 148.11 by atom % calculation |
| Mass Shift | M+1 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-Glutamic acid-15N used for?
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L-Glutamic acid-15N is primarily used in biomolecular NMR spectroscopy, proteomics, and for tracing metabolic pathways due to its stable 15N isotope enrichment.
What are the CAS number and chemical formula for L-Glutamic acid-15N?
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The CAS number is 21160-87-2, and the chemical formula is HO2C(CH2)2CH(15NH)CO2H.
What grade and purity does Tech Serve Solutions supply for L-Glutamic acid-15N?
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Tech Serve Solutions supplies L-Glutamic acid-15N with a purity of 98 atom % 15N. We do not represent this product as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product data.
How should L-Glutamic acid-15N be handled?
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L-Glutamic acid-15N has a GHS hazard classification of WGK Germany 3. Handle with appropriate laboratory precautions to avoid exposure.
Is L-Glutamic acid-15N a controlled substance?
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The provided data does not indicate that L-Glutamic acid-15N is a controlled substance.
How is L-Glutamic acid-15N packed and exported?
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L-Glutamic acid-15N is packed and exported according to industry best practices for chemical reagents and fine chemicals, ensuring safe transit.
How can I request a sample or quote for L-Glutamic acid-15N?
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To request a sample or a quotation for L-Glutamic acid-15N, please contact our sales team through the TSS website or via direct inquiry.
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