α-Ketoglutaric acid sodium salt
α-Ketoglutaric acid sodium salt (CAS 22202-68-2) is a biochemical reagent with the linear formula HOOCCH<sub>2</sub>CH<sub>2</sub>COCOONa and a molecular weight of 168.08 g/mol. This compound serves as a crucial substrate in various enzymatic reactions, particularly those involved in cellular metabolism. It is widely utilized in research settings for studies concerning cancer metabolism, cell biology, and enzyme kinetics.
- IUPAC
- 2-Oxoglutaric acid monosodium salt,2-Oxopentanedioic acid monosodium salt,Sodium 2-oxoglutarate monobasic
- Synonyms
- 2-Oxoglutaric acid monosodium salt2-Oxopentanedioic acid monosodium saltSodium 2-oxoglutarate monobasic
Enzyme Substrate Studies
This compound functions as a substrate for enzymes such as Isocitrate Dehydrogenase (IDH) and Ketoglutarate Dehydrogenase. Its use is integral to understanding enzyme mechanisms and kinetics in biochemical research.
Cancer Metabolism Research
As a key intermediate in the Krebs cycle, α-Ketoglutaric acid sodium salt is employed in studies investigating metabolic pathways altered in cancer cells. This helps researchers explore potential therapeutic targets.
Cell Biology Investigations
The compound is valuable in cell biology research for studying metabolic processes, cellular energy production, and the regulation of key biochemical pathways within cells.
| Molecular weight | 168.08 |
|---|---|
| Linear formula | HOOCCH2CH2COCOONa |
| Assay | ≥98% (enzymatic) |
| Solubility | H2O: soluble0.5 M, clear, colorless |
| Storage temperature | 2-8°C |
| Impurities tested | ≤0.0005% Phosphorus (P)≤0.1% Insoluble matter |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | Al: ≤0.0005%Ca: ≤0.001%Cu: ≤0.0005%Fe: ≤0.0005%K: ≤0.005%Mg: ≤0.0005%NH4+: ≤0.05%Pb: ≤0.001%Zn: ≤0.0005% |
| Anion traces | chloride (Cl-): ≤0.05%sulfate (SO42-): ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioUltra |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is α-Ketoglutaric acid sodium salt used for?
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α-Ketoglutaric acid sodium salt is primarily used as an enzyme substrate in biochemical and cell biology research, particularly in studies related to cancer metabolism and enzymatic pathways.
What is the CAS number and formula for α-Ketoglutaric acid sodium salt?
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The CAS number is 22202-68-2, and its linear formula is HOOCCH<sub>2</sub>CH<sub>2</sub>COCOONa.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies α-Ketoglutaric acid sodium salt with an assay of ≥98% (enzymatic). This product is intended for research and laboratory use and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should α-Ketoglutaric acid sodium salt be handled and stored?
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This compound requires storage at 2-8°C. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 or P1 respirator filter, should be used during handling to mitigate risks.
How is α-Ketoglutaric acid sodium salt packed and shipped?
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Tech Serve Solutions specialises in the global supply and export of fine chemicals, ensuring appropriate packaging and compliance with shipping regulations for all its products.
How can I request a quote or sample for α-Ketoglutaric acid sodium salt?
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To request a quote or sample, please contact our sales team through the website or by calling our office. We are happy to assist with your research needs.
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