JTV-519 hemifumarate

CAS 145903-06-6 (free base)C25H32N2O2S · .5C4H4O4Cell Biology

JTV-519 hemifumarate (CAS: 145903-06-6) is a chemical compound with the formula C25H32N2O2S · .5C4H4O4 and a molecular weight of 482.63. Supplied as a white to beige powder, it is primarily utilised in cell biology research, particularly within cell signalling and neuroscience studies. Its function relates to the regulation of intracellular calcium, making it a valuable reagent for investigating calcium signalling pathways in biological systems. TSS offers this compound with an assay of ≥98% (HPLC).

IUPAC: 1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone hemifumarate,K201 hemifumarate
Synonyms: K201 hemifumarate1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone hemifumarate

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JTV-519 hemifumarate (C25H32N2O2S · .5C4H4O4) — chemical structure, CAS 145903-06-6 (free base); Life Science, fine chemical supplied by Tech Serve Solutions

Cell Biology

01 /Applications

Cell Biology Research

JTV-519 hemifumarate serves as a tool in fundamental cell biology investigations. It is employed to study cellular processes, particularly those involving intracellular calcium dynamics and their impact on cell behaviour.

Cell Signalling Studies

This compound is utilised in research focused on understanding cellular communication pathways. Its ability to modulate intracellular calcium makes it relevant for dissecting complex cell signalling cascades.

Neuroscience Research

In neuroscience, JTV-519 hemifumarate can be applied to investigate neuronal function and the role of calcium signalling in neural processes. This aids in understanding the mechanisms underlying neurological activity.

Intracellular Calcium Regulation

As an intracellular calcium regulator, this compound is valuable for experiments aiming to elucidate the specific mechanisms and consequences of calcium ion flux within cells.

02 /Properties

Molecular weight	482.63
Empirical formula	C25H32N2O2S · .5C4H4O4
Assay	≥98% (HPLC)
Form	powder
Colour	white to beige
Solubility	DMSO: soluble10 mg/mL, clear
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Environmental hazard (GHS09) — Environmental hazard

Warning

Hazard statements

H410Very toxic to aquatic life with long-lasting effects

Precautionary statements

P273Avoid release to the environment
P501Dispose of contents and container per local regulations

Transport (UN / ADR)	UN 3077 9 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	N
Risk statements (R)	50/53
Safety statements (S)	60-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

145903-06-6 (free base)

05 /Additional specifications

Storage Condition	desiccated

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is JTV-519 hemifumarate used for?

JTV-519 hemifumarate is used in cell biology, cell signalling, neuroscience research, and for studying intracellular calcium regulation.

What is the CAS number and formula for JTV-519 hemifumarate?

The CAS number for the free base is 145903-06-6. The empirical formula is C25H32N2O2S · .5C4H4O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies JTV-519 hemifumarate with an assay of ≥98% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.

How should JTV-519 hemifumarate be handled and stored?

JTV-519 hemifumarate is classified under GHS09 with the hazard statement H410 (Very toxic to aquatic life with long lasting effects). It should be handled with appropriate personal protective equipment. Store desiccated at 2-8°C.

How is JTV-519 hemifumarate packed and shipped?

JTV-519 hemifumarate is supplied as a powder. It is eligible for UN 3077 (Environmentally hazardous substance, solid, n.o.s.) 9 / PGIII transport and is exported globally by TSS.