Isopropylmagnesium bromide solution
Isopropylmagnesium bromide solution (CAS 920-39-8) is a highly reactive organometallic compound with the molecular formula (CH3)2MgBr and a molecular weight of 147.30 g/mol. Supplied as a 2.9 M solution in 2-methyltetrahydrofuran, it is an essential reagent in organic synthesis, particularly for Grignard reactions, enabling carbon-carbon bond formation and introducing isopropyl groups into various molecular structures. Its utility spans complex molecule synthesis and the preparation of advanced chemical intermediates.
Grignard Reagent
Serves as a potent Grignard reagent for nucleophilic addition to carbonyl compounds (aldehydes, ketones, esters) and epoxides, facilitating the synthesis of secondary and tertiary alcohols.
Carbon-Carbon Bond Formation
Effectively used in coupling reactions to form new carbon-carbon bonds, crucial for building complex organic frameworks in pharmaceutical and fine chemical synthesis.
Introduction of Isopropyl Groups
A valuable tool for regioselectively installing isopropyl groups onto diverse organic substrates, a common structural motif in many bioactive molecules.
Organometallic Synthesis
A key component in various organometallic transformations, enabling unique synthetic pathways not easily accessible by other reagents.
| Molecular weight | 147.30 |
|---|---|
| Linear formula | (CH3)2MgBr |
| Density | 1.112 g/mL at 25 °C |
| Concentration | 2.9 M in 2-methyltetrahydrofuran40 % (w/w) |
Hazard statements
- H225Highly flammable liquid and vapour
- H260In contact with water releases flammable gases
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P222Do not allow contact with air
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P422
| Flash point | -30 °C / -22 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14/15-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-43-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Isopropylmagnesium bromide solution used for?
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Isopropylmagnesium bromide solution is primarily used as a Grignard reagent in organic synthesis for carbon-carbon bond formation and the introduction of isopropyl groups into molecules. It is essential for creating secondary and tertiary alcohols and building complex organic structures.
What are the CAS number and chemical formula for Isopropylmagnesium bromide solution?
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The CAS number for Isopropylmagnesium bromide solution is 920-39-8, and its chemical formula is (CH3)2MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Isopropylmagnesium bromide solution at a concentration of 2.9 M in 2-methyltetrahydrofuran. We do not represent this product as USP, BP, or EP grade.
How should Isopropylmagnesium bromide solution be handled safely?
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Isopropylmagnesium bromide solution is highly flammable, reacts violently with water, and can cause severe skin burns and eye damage. It may form explosive peroxides and is harmful if inhaled. Handle under an inert atmosphere, away from ignition sources, and use appropriate personal protective equipment, including flame-retardant clothing and respiratory protection. Refer to the Safety Data Sheet for detailed handling instructions.
How is Isopropylmagnesium bromide solution packed and shipped?
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This reagent is supplied in 25mL Sure/Seal bottles designed for safe handling and transfer under inert conditions. It is packed and shipped according to stringent safety regulations for hazardous materials.
How can I request a quote or sample?
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To request a quote or sample of Isopropylmagnesium bromide solution, please use the 'Request a Quote' or 'Request a Sample' button on our website, or contact our sales team directly.
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