Hydroxylamine solution
Hydroxylamine solution (CAS: 7803-49-8, Formula: NH2OH) is a versatile chemical reagent offered by Tech Serve Solutions. This compound, with a molecular weight of 33.03 g/mol, is primarily utilised in chemical synthesis for the preparation of various organic molecules. Its applications span the development of cardiovascular agents, anti-cancer drugs, and antimicrobial compounds, showcasing its importance in pharmaceutical research and development.
- IUPAC
- HDA
Preparation of Prodrugs
Hydroxylamine solution serves as a key reactant in synthesising prodrugs, such as Nω-hydroxy-L-arginine (NOHA), a nitric oxide precursor relevant for cardiovascular applications.
Synthesis of Anti-cancer Agents
It is employed in the preparation of hydroxyaminoguanidines, a class of compounds investigated for their potential as anti-cancer therapeutic agents.
Development of Glucocorticoid Receptor Agonists
This reagent is utilised in the synthesis of nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists, which are studied for their effects on transactivation pathways like PEPCK.
Enhancing Antimicrobial Properties
Hydroxylamine solution is used to create carboxamide derivatives of ofloxacin, aiming to improve the antimicrobial efficacy of these compounds.
Creation of TNF-α Inhibitor Analogues
It facilitates the synthesis of analogues of coumarin-based TNF-α converting enzyme (TACE) inhibitors, contributing to research in anti-inflammatory agents.
Synthesis of HIV Integrase Inhibitors
The compound is a precursor in the development of inhibitors targeting HIV integrase, an important aspect of antiviral drug research.
| Molecular weight | 33.03 |
|---|---|
| Linear formula | NH2OH |
| Assay | 99.999% |
| Boiling point | 107 °C |
| Density | 1.078 g/mL at 25 °C |
| Concentration | 50 wt. % in H2O |
| Application | Reactant for preparation of:• Prodrug for cardiovascular agent Nω-hydroxy-L-arginine (NOHA, nitric oxide precursor)1• Hydroxyaminoguanidines as anti-cancer agents2• Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced phosphoenolpyruvate caboxykinase (PEPCK) transactivation3• Carboxamide derivatives of ofloxacin with improved antimicrobial properties4• Analogues of coumarin based TNF-α converting enzyme (TACE) inhibitors5• HIV integrase inhibitors6 |
Hazard statements
- H290May be corrosive to metals
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H318Causes serious eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
- H373May cause damage to organs through prolonged exposure
- H400Very toxic to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3082 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn,N |
| Risk statements (R) | 5-21/22-37/38-40-41-43-48/22-50 |
| Safety statements (S) | 26-36/37/39-46-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hydroxylamine solution used for?
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Hydroxylamine solution (CAS: 7803-49-8, Formula: NH2OH) is used as a reactant in chemical synthesis for preparing various compounds, including cardiovascular agents, anti-cancer drugs, and antimicrobial agents.
What are the CAS number and formula for Hydroxylamine solution?
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The CAS number for Hydroxylamine solution is 7803-49-8, and its chemical formula is NH2OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hydroxylamine solution with an assay of 99.999%. We do not represent this product as USP, BP, EP, or any pharmacopoeial grade unless explicitly stated in the product specifications.
How should Hydroxylamine solution be handled safely?
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Hydroxylamine solution is hazardous; it can cause severe skin burns and eye damage, is harmful if swallowed or inhaled, and may cause an allergic skin reaction and affect fertility or the unborn child. Always use appropriate personal protective equipment, including eyeshields, gloves, and a full-face respirator, and handle in a well-ventilated area.
How is Hydroxylamine solution packed, shipped, and exported?
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Hydroxylamine solution is carefully packed according to international shipping regulations for hazardous materials. Tech Serve Solutions, as a specialist global supplier and exporter, ensures compliant shipping worldwide.
How can I request a quote or sample of Hydroxylamine solution?
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To request a quote or a sample of Hydroxylamine solution, please contact our sales team through the website or direct email, providing your contact details and requirements.
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